Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50028044
Target5-hydroxytryptamine receptor 3A(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50007872(BIMU 1 | CHEMBL62023 | CHEMBL544755 | 3-Ethyl-2-ox...)
Affinity DataKi:  1nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.45nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 4(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50007872(BIMU 1 | CHEMBL62023 | CHEMBL544755 | 3-Ethyl-2-ox...)
Affinity DataKi:  13nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255827(9-benzyl-9-azabicyclo[3.3.1]nonan-3-yl 2-methoxy-5...)
Affinity DataKi:  92.5nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255707(9-(4-Methoxybenzyl)-9-azabicyclo[3.3.1]nonan-3-yl-...)
Affinity DataKi:  323nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255764(9-(4-Methoxyphenethyl)-9-azabicyclo[3.3.1]nonan-3-...)
Affinity DataKi:  447nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255827(9-benzyl-9-azabicyclo[3.3.1]nonan-3-yl 2-methoxy-5...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT3 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255827(9-benzyl-9-azabicyclo[3.3.1]nonan-3-yl 2-methoxy-5...)
Affinity DataKi: >1.00E+3nMAssay Description:Binding affinity to 5HT4 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255655(9-Allyl-9-azabicyclo[3.3.1]nonan-3-yl 2-methoxy-5-...)
Affinity DataKi:  1.26E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255709(WC-26 | 9-(4-(Dimethylamino)benzyl)-9-azabicyclo[3...)
Affinity DataKi:  1.44E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255656(9-((Pyridine-4-yl)methyl)-9-azabicyclo[3.3.1]nonan...)
Affinity DataKi:  1.56E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255708(9-(4-(2-Fluoroethyl)benzyl)-9-azabicyclo[3.3.1]non...)
Affinity DataKi:  1.71E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255766(9-(4-(Dimethylamino)phenethyl)-9-azabicyclo[3.3.1]...)
Affinity DataKi:  1.87E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255654(9-(2-Fluoroethyl)-9-azabicyclo[3.3.1]nonan-3-yl-2-...)
Affinity DataKi:  2.00E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255706(9-(4-(Methylthio)benzyl)-9-azabicyclo[3.3.1]nonan-...)
Affinity DataKi:  2.02E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255657(9-((Pyridine-3-yl)methyl)-9-azabicyclo[3.3.1]nonan...)
Affinity DataKi:  2.35E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255658(9-((6-Fluoropyridine-3-yl)methyl)-9-azabicyclo[3.3...)
Affinity DataKi:  2.51E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255765(9-(4-(2-Fluoroethyl)phenethyl)-9-azabicyclo[3.3.1]...)
Affinity DataKi:  2.63E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50255828(N-(4-(6,7-dihydroperoxy-3,4-dihydroisoquinolin-2(1...)
Affinity DataKi:  3.08E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Washington University

Curated by ChEMBL
LigandPNGBDBM50007872(BIMU 1 | CHEMBL62023 | CHEMBL544755 | 3-Ethyl-2-ox...)
Affinity DataKi:  6.30E+3nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1-type opioid receptor in guinea pig brain homogenatesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed