Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50027947
TargetSodium/nucleoside cotransporter 2(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CNT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSodium/nucleoside cotransporter 1(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataIC50: 2.50E+5nMAssay Description:Inhibition of human CNT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity to human ENT1 assessed as [3H]uridine uptake by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50255978(1-(2-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl...)
Affinity DataKi:  2.88E+3nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256080((2S,3R,4S,5S,6R)-2-(3,5-dihydroxy-2-(3-(4-hydroxyp...)
Affinity DataKi:  1.24E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256749(1-(2-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl...)
Affinity DataKi:  1.24E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataKi:  1.60E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256125(2-(3-(4-hydroxyphenyl)propyl)benzene-1,3,5-triol |...)
Affinity DataKi:  3.00E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256077(1-(2,4-dihydroxy-6-((2R,3R,4S,5S,6R)-3,4,5-trihydr...)
Affinity DataKi:  3.08E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM23446(3-(4-hydroxyphenyl)-1-(2,4,6-trihydroxyphenyl)prop...)
Affinity DataKi:  3.23E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50255981(1-(2-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl...)
Affinity DataKi:  4.21E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256076(1-(2-hydroxy-6-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-...)
Affinity DataKi:  5.39E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM23617(NBTI | Nitrobenzylthioinosine | CHEMBL418509 | (2R...)
Affinity DataKi:  8.81E+4nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50255979(1-(2-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50250379(1-(2-hydroxyphenyl)-3-phenylpropan-1-one | dihydro...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50249071(2, 6-dihydroxyacetophenone | 2,6-dihydroxy acetoph...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50255980(3, 5-dihydroxyacetophenone | CHEMBL507042)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50241221(1-(2,4-dihydroxyphenyl)ethanone | 2',4'-dihydroxya...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50249070(2,4,6-trihydroxy acetophenone | 2, 4, 6-trihydroxy...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256013(1-(3-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256078(1-(3-hydroxy-5-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256079(1-(2-hydroxy-4-((2R,3R,4S,5S,6R)-3,4,5-trihydroxy-...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSolute carrier family 28 member 3(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50256748(1-(2,6-dihydroxy-4-((2S,3R,4S,5S,6R)-3,4,5-trihydr...)
Affinity DataKi: >1.00E+5nMAssay Description:Binding affinity to human recombinant CNT3 expressed in pig PK15NTD cells assessed as [3H]uridine uptake by beta-scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM20875(CHEMBL245067 | JMC511145 Compound 1 | 1-(2,4-dihyd...)
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity to human ENT1 assessed as [3H]uridine uptake by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEquilibrative nucleoside transporter 1(Human)
University of Tennessee Health Sciences Center

Curated by ChEMBL
LigandPNGBDBM50255978(1-(2-((2S,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl...)
Affinity DataKi: >1.00E+6nMAssay Description:Binding affinity to human ENT1 assessed as [3H]uridine uptake by flow cytometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed