Compile Data Set for Download or QSAR
Report error Found 55 Enz. Inhib. hit(s) with all data for entry = 50027946
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256715(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256714(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256723(9-phenyl-8-(4-((4-(4-(pyridin-2-yl)-1H-imidazol-1-...)
Affinity DataIC50: 2.80nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256723(9-phenyl-8-(4-((4-(4-(pyridin-2-yl)-1H-imidazol-1-...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256718(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 4nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256719(3-methyl-9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,...)
Affinity DataIC50: 4.60nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256718(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256715(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256717(1-(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-tr...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256714(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256721(3-((4-methylpiperazin-1-yl)methyl)-9-phenyl-8-(4-(...)
Affinity DataIC50: 9.90nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256718(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256716(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256716(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 10.4nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256720(3-(chloromethyl)-9-phenyl-8-(4-((4-(5-(pyridin-2-y...)
Affinity DataIC50: 10.5nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256719(3-methyl-9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,...)
Affinity DataIC50: 14.6nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256722(2-((9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-t...)
Affinity DataIC50: 17nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256716(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256714(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 18.1nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256723(9-phenyl-8-(4-((4-(4-(pyridin-2-yl)-1H-imidazol-1-...)
Affinity DataIC50: 18.3nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256717(1-(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-tr...)
Affinity DataIC50: 24.1nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256719(3-methyl-9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,...)
Affinity DataIC50: 24.6nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256720(3-(chloromethyl)-9-phenyl-8-(4-((4-(5-(pyridin-2-y...)
Affinity DataIC50: 26.7nMAssay Description:Inhibition of human cloned Akt1 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256715(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 27nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256718(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 41nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256722(2-((9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-t...)
Affinity DataIC50: 41.8nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256714(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 47.7nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256721(3-((4-methylpiperazin-1-yl)methyl)-9-phenyl-8-(4-(...)
Affinity DataIC50: 55.1nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256721(3-((4-methylpiperazin-1-yl)methyl)-9-phenyl-8-(4-(...)
Affinity DataIC50: 62.5nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256723(9-phenyl-8-(4-((4-(4-(pyridin-2-yl)-1H-imidazol-1-...)
Affinity DataIC50: 74.8nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256722(2-((9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-t...)
Affinity DataIC50: 77.9nMAssay Description:Inhibition of human cloned Akt2 expressed in Drosophila S2 cells by HTRF assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256716(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 108nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256720(3-(chloromethyl)-9-phenyl-8-(4-((4-(5-(pyridin-2-y...)
Affinity DataIC50: 114nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256715(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 168nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256719(3-methyl-9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,...)
Affinity DataIC50: 177nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256722(2-((9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-t...)
Affinity DataIC50: 251nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256717(1-(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-tr...)
Affinity DataIC50: 266nMAssay Description:Inhibition of Akt1 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256721(3-((4-methylpiperazin-1-yl)methyl)-9-phenyl-8-(4-(...)
Affinity DataIC50: 376nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256720(3-(chloromethyl)-9-phenyl-8-(4-((4-(5-(pyridin-2-y...)
Affinity DataIC50: 483nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256717(1-(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-tr...)
Affinity DataIC50: 1.21E+3nMAssay Description:Inhibition of Akt2 by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256720(3-(chloromethyl)-9-phenyl-8-(4-((4-(5-(pyridin-2-y...)
Affinity DataIC50: 2.02E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256719(3-methyl-9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,...)
Affinity DataIC50: 2.78E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256715(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 5.31E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256714(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256713(CHEMBL507130 | CHEMBL262341 | 3-phenyl-2-(4-((4-(5...)
Affinity DataIC50: 5.61E+3nMAssay Description:Inhibition of human ERG expressed in HEK cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetPotassium voltage-gated channel subfamily H member 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256718(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human ERG expressed in HEK cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256714(9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-triaz...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256722(2-((9-phenyl-8-(4-((4-(5-(pyridin-2-yl)-1H-1,2,4-t...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256721(3-((4-methylpiperazin-1-yl)methyl)-9-phenyl-8-(4-(...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50256720(3-(chloromethyl)-9-phenyl-8-(4-((4-(5-(pyridin-2-y...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of SGKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
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