Compile Data Set for Download or QSAR
Report error Found 67 Enz. Inhib. hit(s) with all data for entry = 50027771
LigandPNGBDBM50174298(3-(4-(3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl)bicy...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273862(N-(5-Hydroxy-adamantan-2-yl)-2-m-tolyl-isobutyrami...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50202102(N-[(E)-5-hydroxy-2-adamantyl]-2-{4-[5-(trifluorome...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273859(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273861(N-(3-((4aS,8aR)-decahydroquinoline-1-carbonyl)phen...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273455(2-[(S)-1-(2-Chlorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273858(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataIC50: 32nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273458((S)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataIC50: 34nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273456((S)-5-(2-Hydroxypropan-2-yl)-5-methyl-2-{1-[2-(tri...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273458((S)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataIC50: 45nMAssay Description:Inhibition of dog 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273857(2-((S)-1-(4-fluorophenyl)ethylamino)-5-(2-hydroxyp...)
Affinity DataIC50: 51nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273822(5-(4-Fluorophenyl)-2-[(S)-1-(4-fluorophenyl)ethyla...)
Affinity DataIC50: 53nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273454(2-[(S)-1-(2-Fluorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273403(2-[(S)-1-(4-Chlorophenyl)ethylamino]-5-(3-hydroxyp...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273398(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methyl-4...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273855(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-[4-(hydroxy...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273825(1-(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methy...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273827(2-{(S)-[1-(4-fluorophenyl)ethyl]amino}-5-[4-(2-hyd...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273458((S)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataIC50: 140nMAssay Description:Inhibition of mouse 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273405(2-[(S)-1-(3-Fluorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50167718(2-(phenylsulfonyl)-1-(4-(trifluoromethyl)phenyl)et...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273457((R)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataIC50: 300nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273856(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydroxy-...)
Affinity DataIC50: 310nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273458((S)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataIC50: 340nMAssay Description:Inhibition of rat 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273824(3-(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methy...)
Affinity DataIC50: 680nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273857(2-((S)-1-(4-fluorophenyl)ethylamino)-5-(2-hydroxyp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cells using [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273859(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cells using [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273858(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cells using [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273456((S)-5-(2-Hydroxypropan-2-yl)-5-methyl-2-{1-[2-(tri...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cells using [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273455(2-[(S)-1-(2-Chlorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cells using [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273454(2-[(S)-1-(2-Fluorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human 11beta-HSD2 expressed in CHO cells using [3H]cortisol by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273458((S)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataKi:  12nMAssay Description:Inhibition of dog recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM13754((5S)-2-{[(1S)-1-(2-fluorophenyl)ethyl]amino}-5-met...)
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273822(5-(4-Fluorophenyl)-2-[(S)-1-(4-fluorophenyl)ethyla...)
Affinity DataKi:  22nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273456((S)-5-(2-Hydroxypropan-2-yl)-5-methyl-2-{1-[2-(tri...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273859(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataKi:  25nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273455(2-[(S)-1-(2-Chlorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataKi:  26nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273821(Methyl 4-{2-[(S)-1-(4-fluorophenyl)ethylamino]-5-m...)
Affinity DataKi:  26nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273452(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methyl-5-[4...)
Affinity DataKi:  28nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273825(1-(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methy...)
Affinity DataKi:  30nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273454(2-[(S)-1-(2-Fluorophenyl)ethylamino]-5-(2-hydroxyp...)
Affinity DataKi:  34nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273458((S)-2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(2-hydr...)
Affinity DataKi:  35nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273398(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methyl-4...)
Affinity DataKi:  44nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273855(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-[4-(hydroxy...)
Affinity DataKi:  46nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273858(2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-(1-hydroxyc...)
Affinity DataKi:  49nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273824(3-(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methy...)
Affinity DataKi:  60nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273857(2-((S)-1-(4-fluorophenyl)ethylamino)-5-(2-hydroxyp...)
Affinity DataKi:  65nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273451(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methyl-4...)
Affinity DataKi:  76nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273827(2-{(S)-[1-(4-fluorophenyl)ethyl]amino}-5-[4-(2-hyd...)
Affinity DataKi:  79nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50273823(2-(4-{2-[(S)-1-(4-Fluorophenyl)ethylamino]-5-methy...)
Affinity DataKi:  83nMAssay Description:Inhibition of human recombinant 11beta-HSD1 expressed in Escherichia coli using [3H]cortisone by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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