Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 3107
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28104(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28091(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28105(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28112(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 13nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28110(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 14nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28106(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28111(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 15nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28115(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 16nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28114(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 16nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28109({2-[4-(3-{[4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1...)
Affinity DataIC50: 17nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28095(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28107(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 20nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28098(7-{3-[tert-butyl(2-hydroxyethyl)amino]propoxy}-4-(...)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28088(4-({3-chloro-4-[(1,4,5-trimethyl-1H-imidazol-2-yl)...)
Affinity DataIC50: 26nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28096(7-({3-[bis(2-hydroxyethyl)amino]propyl}amino)-4-({...)
Affinity DataIC50: 26nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28099(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28092(4-({3-bromo-4-[(1,4,5-trimethyl-1H-imidazol-2-yl)s...)
Affinity DataIC50: 30nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28103(N-(3-{[4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-im...)
Affinity DataIC50: 31nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28101(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 32nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28100(4-(3-{[4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-im...)
Affinity DataIC50: 45nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28113(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 47nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28118(CHEMBL103045 | 4-({3-chloro-4-[(1-methyl-1H-imidaz...)
Affinity DataIC50: 50nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28089(4-({4-[(1-benzyl-4,5-dimethyl-1H-imidazol-2-yl)sul...)
Affinity DataIC50: 65nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28123(CHEMBL318804 | 4-({3-chloro-4-[(1-methyl-1H-imidaz...)
Affinity DataIC50: 66nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28108(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 67nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28117(4-[(3-chloro-4-{[4,5-dimethyl-1-(propan-2-yl)-1H-i...)
Affinity DataIC50: 79nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28119(CHEMBL323515 | 4-({3-chloro-4-[(1-methyl-1H-imidaz...)
Affinity DataIC50: 88nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28102(ethyl 1-(3-{[4-({3-chloro-4-[(1-ethyl-4,5-dimethyl...)
Affinity DataIC50: 135nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28087(4-({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)sulfany...)
Affinity DataIC50: 140nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28121(4-({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)sulfany...)
Affinity DataIC50: 150nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28120(4-({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)sulfany...)
Affinity DataIC50: 151nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28116(4-({3-chloro-4-[(4,5-dimethyl-1-propyl-1H-imidazol...)
Affinity DataIC50: 189nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28090(4-({3-chloro-4-[(1,5-dimethyl-1H-imidazol-2-yl)sul...)
Affinity DataIC50: 291nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28093(7-{[3-(dimethylamino)propyl]amino}-6-methoxy-4-({4...)
Affinity DataIC50: 394nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28127(4-({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)sulfany...)
Affinity DataIC50: 600nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28126(4-({3-chloro-4-[(1-methyl-1H-imidazol-2-yl)sulfany...)
Affinity DataIC50: 847nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28122(6-methoxy-4-({4-[(1-methyl-1H-imidazol-2-yl)sulfan...)
Affinity DataIC50: 1.00E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28124(6-methoxy-7-[3-(morpholin-4-yl)propoxy]-4-{[4-(phe...)
Affinity DataIC50: 1.09E+3nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28097(N-(3-{[4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-im...)
Affinity DataIC50: 3.88E+3nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28125(4-{[3-chloro-4-(pyridin-2-ylsulfanyl)phenyl]amino}...)
Affinity DataIC50: 1.00E+4nMAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed
TargetInsulin-like growth factor 1 receptor(Human)
Wyeth Research

LigandPNGBDBM28094(4-({3-chloro-4-[(1-ethyl-4,5-dimethyl-1H-imidazol-...)
Affinity DataIC50: 1.37E+4nMpH: 7.5 T: 2°CAssay Description:Assays were performed in microtiter plates in reaction buffer containing biotinylated substrate, ATP, and purified kinase in the presence of test com...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2009
Entry Details Article
PubMed