Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50027663
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM16034(N-[(1S,2R)-1-benzyl-3-(cyclopropylamino)-2-hydroxy...)
Affinity DataIC50: 15nMAssay Description:Inhibition of BACE1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM16034(N-[(1S,2R)-1-benzyl-3-(cyclopropylamino)-2-hydroxy...)
Affinity DataIC50: 29nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254744(N8-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 56nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254714(N7-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 63nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254785(N6-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 89nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254784(N5-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 112nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM16034(N-[(1S,2R)-1-benzyl-3-(cyclopropylamino)-2-hydroxy...)
Affinity DataIC50: 132nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254711(N-((1S,2R)-1-Benzyl-3-cyclopropylamino-2-hydroxy-p...)
Affinity DataIC50: 141nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254712(N-((1S,2R)-1-Benzyl-3-cyclopropylamino-2-hydroxy-p...)
Affinity DataIC50: 158nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254712(N-((1S,2R)-1-Benzyl-3-cyclopropylamino-2-hydroxy-p...)
Affinity DataIC50: 251nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254746(N8-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 262nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254713(N6-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 524nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254745(N7-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 740nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254708(4'-Chloro-biphenyl-3,5-dicarboxylic acid 3-[((1S,2...)
Affinity DataIC50: 811nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254667(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 889nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254747(N4-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 998nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254709(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.12E+3nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254710(5-(1-benzyl-1H-1,2,3-triazol-4-yl)-N1-((2S,3R)-4-(...)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254665(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.58E+3nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254711(N-((1S,2R)-1-Benzyl-3-cyclopropylamino-2-hydroxy-p...)
Affinity DataIC50: 1.77E+3nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254746(N8-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.95E+3nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254745(N7-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254707(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 2.23E+3nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 1(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254666(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of BACE1 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254666(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254667(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254707(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254708(4'-Chloro-biphenyl-3,5-dicarboxylic acid 3-[((1S,2...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254709(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254710(5-(1-benzyl-1H-1,2,3-triazol-4-yl)-N1-((2S,3R)-4-(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254713(N6-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254714(N7-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254744(N8-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254747(N4-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254784(N5-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254785(N6-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBeta-secretase 2(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50254665(N1-((2S,3R)-4-(cyclopropylamino)-3-hydroxy-1-pheny...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of BACE2 expressed in human 293T cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed