Compile Data Set for Download or QSAR
Report error Found 90 Enz. Inhib. hit(s) with all data for entry = 50000783
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009806(CHEMBL20207 | [3-(7-Chloro-benzothiazol-2-ylmethyl...)
Affinity DataIC50: 1nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 1.90nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 1.90nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009763(CHEMBL20024 | [3-(4-Fluoro-benzothiazol-2-ylmethyl...)
Affinity DataIC50: 2nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of aldose reductase (aldo-keto reductase, AKR1B1) isolated from human placenta.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009781(CHEMBL20169 | [3-(5-Bromo-benzothiazol-2-ylmethyl)...)
Affinity DataIC50: 3.10nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009828(CHEMBL20015 | [3-(4-Chloro-benzothiazol-2-ylmethyl...)
Affinity DataIC50: 3.5nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009784(CHEMBL278991 | [3-(5,7-Dichloro-benzothiazol-2-ylm...)
Affinity DataIC50: 4nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009759(CHEMBL20518 | [3-(5-Chloro-7-fluoro-benzothiazol-2...)
Affinity DataIC50: 5nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009750(CHEMBL282689 | [3-(4,7-Difluoro-benzothiazol-2-ylm...)
Affinity DataIC50: 5nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009774(CHEMBL20161 | [3-(5,7-Dimethyl-benzothiazol-2-ylme...)
Affinity DataIC50: 5.90nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009749(CHEMBL416001 | [3-(7-Chloro-5-fluoro-benzothiazol-...)
Affinity DataIC50: 6.20nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009757(CHEMBL20637 | [3-(5,7-Difluoro-benzothiazol-2-ylme...)
Affinity DataIC50: 6.30nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009804(CHEMBL283996 | [3-(5-Fluoro-benzothiazol-2-ylmethy...)
Affinity DataIC50: 6.90nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009829(CHEMBL20197 | [3-(5-Chloro-benzothiazol-2-ylmethyl...)
Affinity DataIC50: 7.10nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009814(CHEMBL20220 | [4-Oxo-3-(7-trifluoromethyl-benzothi...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009810(CHEMBL422927 | [3-(4,5-Difluoro-benzothiazol-2-ylm...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009783(CHEMBL19958 | (3-Benzothiazol-2-ylmethyl-6,7-dichl...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for the inhibition of the rat lens aldose reductase using the substrate as glucose.More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009769(CHEMBL19289 | (4-Oxo-3-thiazolo[5,4-b]pyridin-2-yl...)
Affinity DataIC50: 10nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009775(CHEMBL20693 | (3-Benzothiazol-2-ylmethyl-4-oxo-6-t...)
Affinity DataIC50: 12nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009776(CHEMBL416370 | (3-Benzothiazol-2-ylmethyl-7-bromo-...)
Affinity DataIC50: 12nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009796(CHEMBL20796 | (3-Benzothiazol-2-ylmethyl-6-chloro-...)
Affinity DataIC50: 15nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009755(CHEMBL21038 | [3-(7-Bromo-benzothiazol-2-ylmethyl)...)
Affinity DataIC50: 15nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009780(CHEMBL19701 | [3-(7-Fluoro-5-trifluoromethyl-benzo...)
Affinity DataIC50: 17nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009773(CHEMBL283787 | (3-Benzothiazol-2-ylmethyl-4-oxo-7-...)
Affinity DataIC50: 18nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50006463(CHEMBL21091 | (3-Benzothiazol-2-ylmethyl-4-oxo-3,4...)
Affinity DataIC50: 19nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009801(CHEMBL282263 | [3-(4,7-Dichloro-benzothiazol-2-ylm...)
Affinity DataIC50: 20nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009777(Ponalrestat (statil) | CHEMBL7679 | [3-(4-Bromo-2-...)
Affinity DataIC50: 21nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009793(CHEMBL280168 | [4-Oxo-3-(4-trifluoromethyl-benzoth...)
Affinity DataIC50: 25nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009817(CHEMBL20004 | [3-(6-Bromo-benzothiazol-2-ylmethyl)...)
Affinity DataIC50: 26nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009792(CHEMBL19966 | [3-(5-Methyl-benzothiazol-2-ylmethyl...)
Affinity DataIC50: 26nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009813(CHEMBL20009 | {3-[1-(5-Chloro-benzothiazol-2-yl)-e...)
Affinity DataIC50: 26nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009761(CHEMBL19906 | (3-Benzothiazol-2-ylmethyl-6-methoxy...)
Affinity DataIC50: 26nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009798(CHEMBL284018 | (3-Benzothiazol-2-ylmethyl-7-methyl...)
Affinity DataIC50: 27nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009823(CHEMBL19759 | (3-Benzothiazol-2-ylmethyl-7-methoxy...)
Affinity DataIC50: 28nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009752(CHEMBL20440 | (3-Benzothiazol-2-ylmethyl-5-fluoro-...)
Affinity DataIC50: 30nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009785(CHEMBL20116 | (3-Benzothiazol-2-ylmethyl-6-nitro-4...)
Affinity DataIC50: 33nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009803(CHEMBL20005 | (3-Benzothiazol-2-ylmethyl-7-chloro-...)
Affinity DataIC50: 34nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009802(CHEMBL283151 | {4-Oxo-3-[1-(5-trifluoromethyl-benz...)
Affinity DataIC50: 37nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009788(CHEMBL20685 | 1'-benzo[d][1,3]thiazol-2-ylmethyl-5...)
Affinity DataIC50: 37nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009756(CHEMBL417643 | [3-(5-Hydroxy-benzothiazol-2-ylmeth...)
Affinity DataIC50: 41nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM16452((4-oxo-3-{[5-(trifluoromethyl)-1,3-benzothiazol-2-...)
Affinity DataIC50: 41nMAssay Description:Compound was tested for the inhibition of the rat lens aldose reductase using the substrate as glyceraldehydeMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009794(CHEMBL20304 | (5-Methyl-3-naphtho[1,2-d]thiazol-2-...)
Affinity DataIC50: 42nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009816(CHEMBL282017 | [3-(1-Benzothiazol-2-yl-ethyl)-4-ox...)
Affinity DataIC50: 43nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009824(CHEMBL278522 | (3-Benzothiazol-2-ylmethyl-7-nitro-...)
Affinity DataIC50: 46nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009782(CHEMBL418007 | [3-(5-Methylsulfanyl-benzothiazol-2...)
Affinity DataIC50: 60nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009764(CHEMBL20306 | [3-(5,6-Difluoro-benzothiazol-2-ylme...)
Affinity DataIC50: 68nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009767(2-(4-oxo-3-((6-(trifluoromethyl)benzo[d]thiazol-2-...)
Affinity DataIC50: 70nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAldo-keto reductase family 1 member B1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50009754(CHEMBL20581 | [3-(6-Chloro-benzothiazol-2-ylmethyl...)
Affinity DataIC50: 76nMAssay Description:Compound was tested for the inhibition of the human placental aldose reductase using the substrate as glyceraldehyde.More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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