Compile Data Set for Download or QSAR
Report error Found 40 Enz. Inhib. hit(s) with all data for entry = 50038775
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50: 0.370nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275719(1,4-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)quino...)
Affinity DataIC50: 1.41nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50157597(CHEMBL254016 | CHEMBL222904 | 6-[ethyl-(2-methoxy-...)
Affinity DataIC50: 3.32nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275716(1,1'-(benzo[lmn][3,8]phenanthroline-2,7(1H,3H,6H,8...)
Affinity DataIC50: 4.83nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275722(2,6-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pyr...)
Affinity DataIC50: 7.70nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275721(2,2'-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}-[...)
Affinity DataIC50: 14nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275718(1,4-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pip...)
Affinity DataIC50: 15.9nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50124570(N,N''-(octane-1,8-diyl)bis(6-(ethyl(2-methoxybenzy...)
Affinity DataIC50: 16.1nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 23.1nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275712(6-[Ethyl-(2-methoxybenzyl)amino]-1-(4-{6-[ethyl-(2...)
Affinity DataIC50: 25.7nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275724(2-{6-[Ethyl-(2-methoxybenzyl)amino]hexyl}benzo[de]...)
Affinity DataIC50: 53.5nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275717(1,4-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pip...)
Affinity DataIC50: 68.9nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275720(1,3-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}imi...)
Affinity DataIC50: 72.4nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275719(1,4-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)quino...)
Affinity DataIC50: 95.8nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275721(2,2'-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}-[...)
Affinity DataIC50: 293nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275724(2-{6-[Ethyl-(2-methoxybenzyl)amino]hexyl}benzo[de]...)
Affinity DataIC50: 416nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275720(1,3-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}imi...)
Affinity DataIC50: 876nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275716(1,1'-(benzo[lmn][3,8]phenanthroline-2,7(1H,3H,6H,8...)
Affinity DataIC50: 1.04E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50: 1.91E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 2.01E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275718(1,4-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pip...)
Affinity DataIC50: 2.09E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50124570(N,N''-(octane-1,8-diyl)bis(6-(ethyl(2-methoxybenzy...)
Affinity DataIC50: 2.25E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275722(2,6-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pyr...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275713(cis-6-[Ethyl-(2-methoxybenzyl)amino]hexanoic acid ...)
Affinity DataIC50: 4.16E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275714((+/-)-trans-6-[Ethyl-(2-methoxybenzyl)amino]hexano...)
Affinity DataIC50: 5.47E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM8960(2-[(1-benzylpiperidin-4-yl)methyl]-5,6-dimethoxy-2...)
Affinity DataIC50: 7.42E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50: 8.13E+3nMAssay Description:Inhibition of human recombinant AChE-induced amyloid beta (1-40) aggregation by thioflavin T formation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50157597(CHEMBL254016 | CHEMBL222904 | 6-[ethyl-(2-methoxy-...)
Affinity DataIC50: 8.49E+3nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275715(trans-6-[Ethyl-(2-methoxybenzyl)amino]hexanoic aci...)
Affinity DataIC50: 8.55E+3nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAmyloid-beta precursor protein(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275723(2,7-bis(6-(ethyl(2-methoxybenzyl)amino)hexyl)benzo...)
Affinity DataIC50: 9.69E+3nMAssay Description:Inhibition of self-induced amyloid beta (1-40) aggregation by thioflavin T formation assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275717(1,4-Bis-{6-[ethyl-(2-methoxybenzyl)amino]hexyl}pip...)
Affinity DataIC50: 1.03E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275712(6-[Ethyl-(2-methoxybenzyl)amino]-1-(4-{6-[ethyl-(2...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50067482(CHEMBL11805 | CHEMBL222856 | CHEMBL557586 | N,N''-...)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM31904(Propidium Iodide, 2 | CHEMBL345124 | Propidium | p...)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM10404(galantamine | (1S,12S,14R)-9-methoxy-4-methyl-11-o...)
Affinity DataIC50: 2.07E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275715(trans-6-[Ethyl-(2-methoxybenzyl)amino]hexanoic aci...)
Affinity DataIC50: 2.53E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275713(cis-6-[Ethyl-(2-methoxybenzyl)amino]hexanoic acid ...)
Affinity DataIC50: 3.08E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAcetylcholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM31904(Propidium Iodide, 2 | CHEMBL345124 | Propidium | p...)
Affinity DataIC50: 3.23E+4nMAssay Description:Inhibition of human recombinant AChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCholinesterase(Human)
University of Bologna

Curated by ChEMBL
LigandPNGBDBM50275714((+/-)-trans-6-[Ethyl-(2-methoxybenzyl)amino]hexano...)
Affinity DataIC50: 3.68E+4nMAssay Description:Inhibition of human serum BChE by Ellman's assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed