Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 5616
TargetProstaglandin G/H synthase 1 [582-599](Human)
University of Alexandria

LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 260nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alexandria

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 300nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50: 780nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alexandria

LigandPNGBDBM91685(Pyrazolyl benzenesulfonamide derivative, 9b)
Affinity DataIC50: 920nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alexandria

LigandPNGBDBM91679(Pyrazolyl benzenesulfonamide derivative, 7b)
Affinity DataIC50: 1.26E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alexandria

LigandPNGBDBM91678(Pyrazolyl benzenesulfonamide derivative, 7a)
Affinity DataIC50: 1.35E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Alexandria

LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 2.63E+3nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1 [582-599](Human)
University of Alexandria

LigandPNGBDBM91679(Pyrazolyl benzenesulfonamide derivative, 7b)
Affinity DataIC50: 7.64E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1 [582-599](Human)
University of Alexandria

LigandPNGBDBM91678(Pyrazolyl benzenesulfonamide derivative, 7a)
Affinity DataIC50: 8.36E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1 [582-599](Human)
University of Alexandria

LigandPNGBDBM91685(Pyrazolyl benzenesulfonamide derivative, 9b)
Affinity DataIC50: 9.42E+4nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1 [582-599](Human)
University of Alexandria

LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1 [582-599](Human)
University of Alexandria

LigandPNGBDBM91684(Pyrazolyl benzenesulfonamide derivative, 9a)
Affinity DataIC50: 1.00E+5nMAssay Description:The compounds that exhibited potent anti-inflammatory profiles were futher tested for their ability to inhibit human COX-1 and COX-2 enzymes in-vitro...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/9/2012
Entry Details Article
PubMed