Compile Data Set for Download or QSAR
Report error Found 31 Enz. Inhib. hit(s) with all data for entry = 50030256
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293243(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 1nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293242(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(3-(methy...)
Affinity DataIC50: 2nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293244(N-(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293247(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(3,5-dimo...)
Affinity DataIC50: 2nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293240(N-(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyr...)
Affinity DataIC50: 12nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293248(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 13nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293245(N,N'-(5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)...)
Affinity DataIC50: 15nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293247(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(3,5-dimo...)
Affinity DataIC50: 17nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293241(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 23nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293242(N4-(5-chlorobenzo[d][1,3]dioxol-4-yl)-N2-(3-(methy...)
Affinity DataIC50: 32nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25223(3-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyr...)
Affinity DataIC50: 40nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293249(5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 77nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25226(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-meth...)
Affinity DataIC50: 90nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293239(N2-(3,5-bis(methylsulfonyl)phenyl)-N4-(5-chloroben...)
Affinity DataIC50: 114nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293244(N-(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyr...)
Affinity DataIC50: 170nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25223(3-({4-[(5-chloro-2H-1,3-benzodioxol-4-yl)amino]pyr...)
Affinity DataIC50: 172nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25226(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-(3-meth...)
Affinity DataIC50: 190nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293239(N2-(3,5-bis(methylsulfonyl)phenyl)-N4-(5-chloroben...)
Affinity DataIC50: 209nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293238(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 220nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293246(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 370nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM25229(4-N-(5-chloro-2H-1,3-benzodioxol-4-yl)-2-N-[3-(mor...)
Affinity DataIC50: 580nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293237(N-[3-[[4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYR...)
Affinity DataIC50: 741nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293237(N-[3-[[4-[(5-CHLORO-1,3-BENZODIOXOL-4-YL)AMINO]PYR...)
Affinity DataIC50: 794nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293248(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 887nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293238(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 900nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293240(N-(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyr...)
Affinity DataIC50: 2.05E+3nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293245(N,N'-(5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)...)
Affinity DataIC50: 7.18E+3nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293243(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 1.41E+4nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293241(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 2.22E+4nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293246(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEphrin type-B receptor 4(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293249(5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed