Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 50027348
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274180(N-Formyl-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274021(N-Formyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataIC50: 35nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274019(N-Formyl-L-alanine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataIC50: 43nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274183(5-oxo-L-Proline-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-o...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274181(N-Acetyl-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataIC50: 430nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274056(N-Acetyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataIC50: 460nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274020(N-Formyl-beta-alanine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataIC50: 600nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274779(N-Acetyl-glycine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274182(N-Formyl-L-proline-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274182(N-Formyl-L-proline-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataKi:  1.70E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274020(N-Formyl-beta-alanine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274779(N-Acetyl-glycine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-...)
Affinity DataKi:  2.30E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataKi:  2.50E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274183(5-oxo-L-Proline-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-o...)
Affinity DataKi:  2.60E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of FAAH-mediated [14C]anandamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274019(N-Formyl-L-alanine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataKi:  3.10E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274182(N-Formyl-L-proline-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of FAAH-mediated [14C]anandamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274723(N-Formyl-D-leucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274021(N-Formyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataKi:  5.70E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274180(N-Formyl-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataKi:  6.00E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274020(N-Formyl-beta-alanine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataKi:  6.40E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274181(N-Acetyl-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataIC50: 6.60E+3nMAssay Description:Inhibition of FAAH-mediated [14C]anandamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274182(N-Formyl-L-proline-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataKi:  7.40E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274056(N-Acetyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataKi:  8.40E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274181(N-Acetyl-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataKi:  8.60E+3nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274183(5-oxo-L-Proline-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM24586((1R)-1-{[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]methyl}d...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274181(N-Acetyl-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274056(N-Acetyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274180(N-Formyl-L-isoleucine-(1S)-1-[[(2S,3S)-3-hexyl-4-o...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274021(N-Formyl-L-valine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274779(N-Acetyl-glycine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274019(N-Formyl-L-alanine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in HEK293 cells by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274778(4-Methylpentanoic Acid (1S)-1-[[(2S,3S-3-Hexyl-4-o...)
Affinity DataIC50: 1.04E+4nMAssay Description:Inhibition of FAAH-mediated [14C]anandamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274680(L-Phenylalanine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-o...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274722((3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274215(N-Formyl-L-phenylalanine-(1S)-1-[[(2S,3S)-3-hexyl-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274216(N-[(Phenylmethoxy)carbonyl]-L-phenylalanine-(1S)-1...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274724(N-[(1,1-Dimethylethoxy)carbonyl]-L-leucine-(1S)-1-...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274778(4-Methylpentanoic Acid (1S)-1-[[(2S,3S-3-Hexyl-4-o...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274018(N-[(Phenylmethoxy)carbonyl]-glycine-(1S)-1-[[(2S,3...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274776(L-Leucine-(1S)-1-[[(2S,3S)-3-hexyl-4-oxo-2-oxetany...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274777(N-[(Phenylmethoxy)carbonyl]-D-Leucine-(1S)-1-[[(2S...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetDiacylglycerol lipase-alpha(Human)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274725(N-[(Phenylmethoxy)carbonyl]-L-leucine-(1S)-1-[[(2S...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human recombinant DAGL-alpha-mediated sn-1-[14C]oleoyl-2-arachidonoyl-glycerol hydrolysis to 2-AG overexpressed in african green monkey...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50274722((3S,4S)-3-Hexyl-4-[(2S)-2-hydroxytridecyl]oxetan-2...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FAAH-mediated [14C]anandamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM24567(Tetrahydrolipstatin | CHEMBL175247 | Xenical | (2S...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of FAAH-mediated [14C]anandamide hydrolysis in rat brain membraneMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
Displayed 1 to 50 (of 66 total ) | Next | Last >>
Jump to: