Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50027246
LigandPNGBDBM50275728(N-(4-chlorophenethyl)-2-isobutyl-N-(1,4-dioxaspiro...)
Affinity DataIC50: 1.5nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275644(cis-N-(4-chlorophenethyl)-N-(1-oxaspiro[4.5]decan-...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275896(ethyl 2-(N-(1,4-dioxaspiro[4.5]decan-8-yl)benzo[b]...)
Affinity DataIC50: 5nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275729(N-(4-chlorophenethyl)-2-ethyl-N-(1,4-dioxaspiro[4....)
Affinity DataIC50: 18nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266070(4-(N-(4-chlorophenethyl)benzo[b]thiophene-3-carbox...)
Affinity DataIC50: 31nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275779(N-(2-(4-chlorophenyl)propyl)-N-(1,4-dioxaspiro[4.5...)
Affinity DataIC50: 35nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275573(trans-N-(4-chlorophenethyl)-N-4-hydroxycyclohexyl)...)
Affinity DataIC50: 70nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275605(N-(4-chlorophenethyl)-N-(1,4-dioxaspiro[4.5]decan-...)
Affinity DataIC50: 75nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275683(N-(4-chlorophenethyl)-N-(1,4-dioxaspiro[4.5]decan-...)
Affinity DataIC50: 80nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275897(methyl 2-(N-(1,4-dioxaspiro[4.5]decan-8-yl)benzo[b...)
Affinity DataIC50: 89nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275834(N-(2-(4-chlorophenyl)-2-methylpropyl)-N-(1,4-dioxa...)
Affinity DataIC50: 90nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275777(N-(4-chlorophenethyl)-N-(1,4-dioxaspiro[4.5]decan-...)
Affinity DataIC50: 110nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50266071(N-(4-chlorophenethyl)-N-((1r,4r)-4-hydroxycyclohex...)
Affinity DataIC50: 125nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275608(N-(4-chlorophenethyl)-N-cyclohexylbenzo[b]thiophen...)
Affinity DataIC50: 175nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275727(N-(4-chlorophenethyl)-2-(methoxymethyl)-N-(1,4-dio...)
Affinity DataIC50: 175nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275604(cis-N-(4-chlorophenethyl)-N-(4-hydroxycyclohexyl)b...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275645(trans-N-(4-chlorophenethyl)-N-(1-oxaspiro[4.5]deca...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275570(N-(4-chlorophenethyl)-N-(1-(2,4-difluorophenethyl)...)
Affinity DataIC50: 200nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275898(methyl 2-(N-(1,4-dioxaspiro[4.5]decan-8-yl)benzo[b...)
Affinity DataIC50: 290nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275778(N-(2-chlorophenethyl)-N-(1,4-dioxaspiro[4.5]decan-...)
Affinity DataIC50: 300nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275539(N-(4-chlorophenethyl)-N-(1-(2-(2,4-difluorophenyl)...)
Affinity DataIC50: 330nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275572(N-(4-chlorophenethyl)-N-(4-oxocyclohexyl)benzo[b]t...)
Affinity DataIC50: 350nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275643(N-benzyl-N-(4-chlorophenethyl)benzo[b]thiophene-3-...)
Affinity DataIC50: 370nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275833(N-benzyl-N-(1,4-dioxaspiro[4.5]decan-8-yl)benzo[b]...)
Affinity DataIC50: 395nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275776(N-(4-chlorophenethyl)-N-(1,4-dioxaspiro[4.5]decan-...)
Affinity DataIC50: 400nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275835(N-(2-(4-chlorophenoxy)ethyl)-N-(1,4-dioxaspiro[4.5...)
Affinity DataIC50: 435nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275726(N-(4-chlorophenethyl)-2-isopropoxy-N-(1,4-dioxaspi...)
Affinity DataIC50: 835nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275832(N-(2-(pyridin-2-yl)ethyl)-N-(1,4-dioxaspiro[4.5]de...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275538(N-(4-chlorophenethyl)-N-(1-(3-(4-methoxyphenyl)pro...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275606(N-(6-aminopyridin-3-yl)-N-(4-chlorophenethyl)benzo...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275682(N-(4-chlorophenethyl)-3-methoxy-N-(1,4-dioxaspiro[...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275646(N-(4-chlorophenethyl)-N-(1,4-dioxaspiro[4.5]decan-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275571(N-(4-chlorophenethyl)-N-(piperidin-4-yl)benzo[b]th...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275681(N-(4-chlorophenethyl)-N-(1,4-dioxaspiro[4.5]decan-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275684(N-(4-chlorophenethyl)-2-(methylamino)-N-(1,4-dioxa...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
LigandPNGBDBM50275607(N-(4-chlorophenethyl)-N-(tetrahydro-2H-pyran-4-yl)...)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]r-hC5a from C5a receptor in cAMP differentiated human U937 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed