Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50004447
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 0.117nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 0.171nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 0.281nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 0.296nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 0.306nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of Candida albicans ATCC 90028 glucan synthase at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 0.503nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of Candida albicans ATCC 90028 glucan synthase at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-D-glucan synthase catalytic subunit(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 14.8nMAssay Description:Inhibition of Candida albicans ATCC 90028 glucan synthase at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 27.7nMAssay Description:Inhibition of Candida tropicalis T26 blood stream isolate glucan synthase subunit FKS1p with LLTLSLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 59.6nMAssay Description:Inhibition of Candida tropicalis T26 blood stream isolate glucan synthase subunit FKS1p with LLTLSLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 77nMAssay Description:Inhibition of Candida tropicalis T26 blood stream isolate glucan synthase subunit FKS1p with LLTLSLRDP mutant at monophasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 204nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 223nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478216(CHEBI:600520 | Micafungin | Mycamine)
Affinity DataIC50: 228nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 264nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50417554(ANIDULAFUNGIN)
Affinity DataIC50: 357nMAssay Description:Inhibition of Candida tropicalis T19 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed
Target1,3-beta-glucan synthase(Yeast)
University of Medicine and Dentistry of New Jersey

Curated by ChEMBL
LigandPNGBDBM50478215(CHEBI:474180 | Cancidas | Caspofungin | Caspofungi...)
Affinity DataIC50: 370nMAssay Description:Inhibition of Candida tropicalis T3 blood stream isolate glucan synthase subunit FKS1p with FLTLS/PLRDP mutant at biphasic kineticsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMed