Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 50027134
TargetTransketolase(Human)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263817(5-benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human recombinant transketolase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264033(3-(4-fluorophenyl)-5-(4-methoxyphenyl)-2-methylpyr...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263972(3-(4-chlorophenyl)-5-(4-methoxyphenyl)-2-methylpyr...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263925(5-benzyl-3-(4-chlorophenyl)-2-(trifluoromethyl)pyr...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264091(2-methyl-3,5-diphenyl-6-propylpyrazolo[1,5-a]pyrim...)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264090(2-methyl-5-(naphthalen-2-yl)-3-phenylpyrazolo[1,5-...)
Affinity DataIC50: 1.95E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264092(3-(4-chlorophenyl)-2-ethyl-5-(4-methoxyphenyl)pyra...)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM58242(3-(4-methoxyphenyl)-5-phenyl-2-(trifluoromethyl)py...)
Affinity DataIC50: 2.02E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM51305(SMR000456169 | 3,5-diphenyl-2-(trifluoromethyl)pyr...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264035(2-methyl-3,5-diphenylpyrazolo[1,5-a]pyrimidin-7(4H...)
Affinity DataIC50: 3.06E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263971(3-(4-chlorophenyl)-2-methyl-5-phenylpyrazolo[1,5-a...)
Affinity DataIC50: 3.42E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264037(3-(4-chlorophenyl)-5-((4-chlorophenylthio)methyl)-...)
Affinity DataIC50: 4.14E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263970(3,5-bis(4-methoxyphenyl)-2-methylpyrazolo[1,5-a]py...)
Affinity DataIC50: 4.24E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264034(3-(4-bromophenyl)-5-(2-methoxyphenyl)-2-methylpyra...)
Affinity DataIC50: 5.35E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264036(3-(4-chlorophenyl)-2-methyl-5-((1-phenyl-1H-tetraz...)
Affinity DataIC50: 5.51E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264088(5-((4-chlorophenylthio)methyl)-2-methyl-3-phenylpy...)
Affinity DataIC50: 6.37E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263876(5-benzyl-3-phenyl-2-(trifluoromethyl)pyrazolo[1,5-...)
Affinity DataIC50: 7.11E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263927(methyl 2-(3-(4-bromophenyl)-7-oxo-2-(trifluorometh...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263969(3-(4-methoxyphenyl)-2-methyl-5-phenylpyrazolo[1,5-...)
Affinity DataIC50: 9.07E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263929(3-(4-chlorophenyl)-5-methyl-2-(trifluoromethyl)pyr...)
Affinity DataIC50: 9.84E+4nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263817(5-benzyl-3-(4-chlorophenyl)pyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50: 1.14E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263875(5-(chloromethyl)-3-phenylpyrazolo[1,5-a]pyrimidin-...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263344(3,5-Bis-(4-chloro-phenyl)-7-trifluoromethyl-pyrazo...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263345(3-(3-Bromo-phenyl)-5,7-diphenyl-pyrazolo[1,5-a]pyr...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50264089(3-(4-chlorophenyl)-5-(methoxymethyl)-2-methylpyraz...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263872(3-(4-chlorophenyl)-5-(methoxymethyl)pyrazolo[1,5-a...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM40457(cid_2211071 | UNM000003620201 | CHEMBL522818 | 3-(...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263928(3-(4-bromophenyl)-5-methyl-2-(trifluoromethyl)pyra...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263873(3-(4-chlorophenyl)-5-methylpyrazolo[1,5-a]pyrimidi...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target1-deoxy-D-xylulose-5-phosphate synthase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Illinois At Chicago

Curated by ChEMBL
LigandPNGBDBM50263874(ethyl 2-(5-methyl-7-oxo-3-phenyl-4,7-dihydropyrazo...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of Mycobacterium tuberculosis cloned 1-deoxy-D-xylulose-5-phosphate synthase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed