Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50038658
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50272529(3,7-Bis(2-hydroxyethyl)icaritin | CHEMBL498486)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 75nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50272526(Icariside II | CHEMBL497293)
Affinity DataIC50: 160nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM14390(SILDENAFIL CITRATE | Sildenafil# | CHEMBL192 | 5-[...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human PDE6CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50272528(7-(2-Hydroxyethyl)-3-O-rhamnosylicariin | CHEMBL50...)
Affinity DataIC50: 360nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50240974(8-prenylquercetin | 2-(3,4-Dihydroxy-phenyl)-3,5,7...)
Affinity DataIC50: 700nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50240972(8-prenylapigenin | 5,7-Dihydroxy-2-(4-hydroxy-phen...)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50272527(3-hydroxy-7-o-beta-glucose-8-prenyl-4'-methoxy Chr...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50027363(CHEBI:78420 | Icariin)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM19460(CHEMBL376915 | YS04 | (2S)-5,7-dihydroxy-2-(4-hydr...)
Affinity DataIC50: 1.62E+4nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
LigandPNGBDBM50272529(3,7-Bis(2-hydroxyethyl)icaritin | CHEMBL498486)
Affinity DataIC50: 3.09E+4nMAssay Description:Inhibition of human PDE6CMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Human)
University of Milan

Curated by ChEMBL
LigandPNGBDBM50272557(beta-Anhydroicaritin | 3,7-dimethanesulfonyl-8-pre...)
Affinity DataIC50: 4.55E+4nMAssay Description:Inhibition of human recombinant PDE5A1 expressed in COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/17/2012
Entry Details Article
PubMed