Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 2833
TargetCathepsin S(Human)
Novartis

LigandPNGBDBM25138(7-(2-cyclopentylethyl)-6-[4-(4-acetylpiperazin-1-y...)
Affinity DataIC50: 5nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
Novartis

LigandPNGBDBM25134(CHEMBL481170 | 7-(2-cyclohexylethyl)-6-[4-(4-acety...)
Affinity DataIC50: 9nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
Novartis

LigandPNGBDBM25136(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 9nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Mouse)
Novartis

LigandPNGBDBM25134(CHEMBL481170 | 7-(2-cyclohexylethyl)-6-[4-(4-acety...)
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
Novartis

LigandPNGBDBM25141(7-[2-(4,4-difluorocyclohexyl)ethyl]-6-[4-(4-acetyl...)
Affinity DataIC50: 10nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
Novartis

LigandPNGBDBM25137(7-(2-cyclohexylethyl)-6-[4-(4-acetyl-1,4-diazepan-...)
Affinity DataIC50: 11nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Mouse)
Novartis

LigandPNGBDBM25135(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 14nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
Novartis

LigandPNGBDBM25139(7-[2-(4-chlorophenyl)ethyl]-6-[4-(4-acetylpiperazi...)
Affinity DataIC50: 17nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
Novartis

LigandPNGBDBM25135(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 18nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Mouse)
Novartis

LigandPNGBDBM25141(7-[2-(4,4-difluorocyclohexyl)ethyl]-6-[4-(4-acetyl...)
Affinity DataIC50: 20nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin S(Human)
Novartis

LigandPNGBDBM25140(7-(2-cycloheptylethyl)-6-[4-(4-acetylpiperazin-1-y...)
Affinity DataIC50: 50nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
Novartis

LigandPNGBDBM25138(7-(2-cyclopentylethyl)-6-[4-(4-acetylpiperazin-1-y...)
Affinity DataIC50: 79nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
Novartis

LigandPNGBDBM25137(7-(2-cyclohexylethyl)-6-[4-(4-acetyl-1,4-diazepan-...)
Affinity DataIC50: 290nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
Novartis

LigandPNGBDBM25139(7-[2-(4-chlorophenyl)ethyl]-6-[4-(4-acetylpiperazi...)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
Novartis

LigandPNGBDBM25139(7-[2-(4-chlorophenyl)ethyl]-6-[4-(4-acetylpiperazi...)
Affinity DataIC50: 1.00E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
Novartis

LigandPNGBDBM25137(7-(2-cyclohexylethyl)-6-[4-(4-acetyl-1,4-diazepan-...)
Affinity DataIC50: 1.00E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
Novartis

LigandPNGBDBM25136(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 1.00E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
Novartis

LigandPNGBDBM25136(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
Novartis

LigandPNGBDBM25134(CHEMBL481170 | 7-(2-cyclohexylethyl)-6-[4-(4-acety...)
Affinity DataIC50: 1.65E+3nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
Novartis

LigandPNGBDBM25140(7-(2-cycloheptylethyl)-6-[4-(4-acetylpiperazin-1-y...)
Affinity DataIC50: 2.00E+3nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
Novartis

LigandPNGBDBM25140(7-(2-cycloheptylethyl)-6-[4-(4-acetylpiperazin-1-y...)
Affinity DataIC50: 2.00E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
Novartis

LigandPNGBDBM25138(7-(2-cyclopentylethyl)-6-[4-(4-acetylpiperazin-1-y...)
Affinity DataIC50: 2.30E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
Novartis

LigandPNGBDBM25134(CHEMBL481170 | 7-(2-cyclohexylethyl)-6-[4-(4-acety...)
Affinity DataIC50: 5.20E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
Novartis

LigandPNGBDBM25141(7-[2-(4,4-difluorocyclohexyl)ethyl]-6-[4-(4-acetyl...)
Affinity DataIC50: 5.40E+3nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Human)
Novartis

LigandPNGBDBM25135(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 5.90E+3nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
Novartis

LigandPNGBDBM25141(7-[2-(4,4-difluorocyclohexyl)ethyl]-6-[4-(4-acetyl...)
Affinity DataIC50: 6.20E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Human)
Novartis

LigandPNGBDBM25135(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 6.80E+3nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Rat)
Novartis

LigandPNGBDBM25134(CHEMBL481170 | 7-(2-cyclohexylethyl)-6-[4-(4-acety...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Rat)
Novartis

LigandPNGBDBM25135(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCathepsin K(Rat)
Novartis

LigandPNGBDBM25141(7-[2-(4,4-difluorocyclohexyl)ethyl]-6-[4-(4-acetyl...)
Affinity DataIC50: 1.00E+4nMpH: 7.0 T: 2°CAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Rat)
Novartis

LigandPNGBDBM25134(CHEMBL481170 | 7-(2-cyclohexylethyl)-6-[4-(4-acety...)
Affinity DataIC50: 1.00E+4nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Rat)
Novartis

LigandPNGBDBM25135(7-(2-cyclohexylethyl)-6-[4-(4-acetylpiperazin-1-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProcathepsin L(Rat)
Novartis

LigandPNGBDBM25141(7-[2-(4,4-difluorocyclohexyl)ethyl]-6-[4-(4-acetyl...)
Affinity DataIC50: 1.00E+4nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed