Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 50035969
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50453057(CHEMBL3085527)
Affinity DataIC50: 0.0300nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009242(CHEMBL48565 | {1-[1-Benzyl-4-(2-benzyloxycarbonyla...)
Affinity DataIC50: 0.200nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009261([1-Benzyl-2-hydroxy-4-(2-hydroxy-indan-1-ylcarbamo...)
Affinity DataIC50: 0.300nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009242(CHEMBL48565 | {1-[1-Benzyl-4-(2-benzyloxycarbonyla...)
Affinity DataIC50: 0.400nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229340(CHEMBL3350201)
Affinity DataIC50: 0.400nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009260(CHEMBL73875 | 1N-[4-amino(imino)methylamino-1-carb...)
Affinity DataIC50: 0.780nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009253(2N-(tert-butyl)-1-[3-[2-carbamoyl-1-(2-quinolylcar...)
Affinity DataIC50: 2nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM196(CHEMBL307193 | benzyl N-[(1S)-1-{[(2S,4S)-4-[(2S)-...)
Affinity DataIC50: 3nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009256(2-{1-[1-(2-{1-[1-(1-amino-2-methyl-(1S)-butanamide...)
Affinity DataIC50: 3.5nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009259(1-aminobutyloxycarbonyl-2-phenyl-(1S)-ethyl[2-[1-[...)
Affinity DataIC50: 9nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009257(di-tert-butyl ((2S,3R,4S,5S)-3,4-dihydroxy-1,6-dip...)
Affinity DataIC50: 12nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009249(1N-[1-[1-[1-benzyl-2-[2-[1-[1-carbamoyl-2-methyl-(...)
Affinity DataIC50: 19nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229339(CHEMBL3350613)
Affinity DataIC50: 140nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009248(CHEMBL45627 | (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)...)
Affinity DataIC50: 2.50E+3nMAssay Description:The compound was tested for its affinity against HIV-1 protease in vitroMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009244(CHEMBL9735 | N-((1S,3S)-3-Acetylamino-1-benzyl-2-h...)
Affinity DataIC50: 1.00E+4nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009248(CHEMBL45627 | (2R,3S)-3-((4E,7E)-nona-4,7-dienoyl)...)
Affinity DataIC50: 2.50E+6nMAssay Description:The compound was tested for its affinity against HIV-2 protease (in vitro)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009241(1-[1-[1-aminobutyloxycarbonyl-2-methyl-(1S)-propyl...)
Affinity DataKi:  0.0400nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009258(CHEMBL307236 | 2-[1-[1-carbamoyl-2-methyl-(1S)-pro...)
Affinity DataKi:  0.600nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50229341(CHEMBL3350610)
Affinity DataKi:  0.660nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50212827(CHEMBL3350189)
Affinity DataKi: <1nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKi:  5nMAssay Description:The compound was tested for its affinity against HIV -2 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009252(methyl 2-[1-[7-[1-amino-(1S)-ethylcarboxamido]-4-b...)
Affinity DataKi:  5nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009240(CHEMBL74502 | methyl 2-[1-[4-[1-[1-amino-(1S)-ethy...)
Affinity DataKi:  18nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50368642(ACETYLPEPSTATIN)
Affinity DataKi:  20nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009252(methyl 2-[1-[7-[1-amino-(1S)-ethylcarboxamido]-4-b...)
Affinity DataKi:  35nMAssay Description:The compound was tested for its affinity against HIV-2 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009255(1N-[2-methyl-1-(2-pyridylmethylcarbamoyl)butyl]-5-...)
Affinity DataKi:  70nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  100nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGenome polyprotein(Human rhinovirus B)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  100nMAssay Description:The compound was tested for its affinity against HIV-2 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009245(CHEMBL306261 | 2-[1-[1-carbamoyl-2-methyl-(1S)-pro...)
Affinity DataKi:  450nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009247((S)-2-[(S)-2-((3S,4S)-4-{(S)-2-[(S)-2-((S)-2-Amino...)
Affinity DataKi:  1.20E+3nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM912(PEPSTATIN | Pepstatine | N-[(3-Methyl-1-oxobutyl)-...)
Affinity DataKi:  1.40E+3nMAssay Description:The compound was tested for its affinity against HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009262(1-[1-[1-[1-amino-2-hydroxy-(1S)-ethylcarboxamido]-...)
Affinity DataKi:  4.40E+3nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50009246((S)-2-((S)-2-Acetylamino-3-hydroxy-propionylamino)...)
Affinity DataKi:  3.90E+4nMAssay Description:Binding affinity for HIV-1 proteaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/21/2012
Entry Details Article
PubMed