Compile Data Set for Download or QSAR
Report error Found 66 Enz. Inhib. hit(s) with all data for entry = 2778
LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50: 800nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.00E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)
Affinity DataIC50: 1.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50: 1.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)
Affinity DataIC50: 2.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24542(3-{2-[(3Z)-5-{[(3-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 3.80E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24539((3Z)-N-[(4-chlorophenyl)methyl]-3-[2-(2-nitropheny...)
Affinity DataIC50: 4.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50: 4.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24550(3-{2-[(3Z)-5-{[(3-chloro-4-fluorophenyl)methyl]sul...)
Affinity DataIC50: 4.80E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 5.00E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24551(3-{2-[(3Z)-5-{[2-(2,4-dichlorophenyl)ethyl]sulfamo...)
Affinity DataIC50: 5.20E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 5.50E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 5.90E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 6.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24541(4-{2-[(3Z)-5-(benzylsulfamoyl)-2-oxo-2,3-dihydro-1...)
Affinity DataIC50: 7.10E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24545(4-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 7.40E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 7.50E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24552(4-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 8.30E+3nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50: 9.30E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24539((3Z)-N-[(4-chlorophenyl)methyl]-3-[2-(2-nitropheny...)
Affinity DataIC50: 9.80E+3nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24553(3-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 1.06E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.08E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.13E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24549(4-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.14E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24545(4-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.17E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24538((3Z)-3-[2-(2-nitrophenyl)hydrazin-1-ylidene]-2-oxo...)
Affinity DataIC50: 1.19E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.45E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24542(3-{2-[(3Z)-5-{[(3-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.54E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24533((3Z)-3-[2-(2-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50: 1.54E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50: 1.57E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24534((3Z)-3-[2-(3-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50: 1.58E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.59E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.80E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24544(4-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.81E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24548(3-{2-[(3Z)-5-{[(4-fluorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.83E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24543(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.88E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24551(3-{2-[(3Z)-5-{[2-(2,4-dichlorophenyl)ethyl]sulfamo...)
Affinity DataIC50: 1.93E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24546(3-{2-[(3Z)-5-{[(2-chlorophenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 1.94E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24535(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]carbamoyl}-2...)
Affinity DataIC50: 1.94E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24535(3-{2-[(3Z)-5-{[(4-chlorophenyl)methyl]carbamoyl}-2...)
Affinity DataIC50: 2.23E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 2.29E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 2.57E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24537(4-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50: 2.77E+4nMpH: 7.0 T: 2°CAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24547(2-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 3.24E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM24540(3-{2-[(3Z)-5-{[(4-methylphenyl)methyl]sulfamoyl}-2...)
Affinity DataIC50: 3.26E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24552(4-{2-[(3Z)-5-({[4-chloro-3-(trifluoromethyl)phenyl...)
Affinity DataIC50: 3.28E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24536(3-{2-[(3Z)-2-oxo-5-(propan-2-ylsulfamoyl)-2,3-dihy...)
Affinity DataIC50: 3.71E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Moffitt Cancer Center

LigandPNGBDBM24534((3Z)-3-[2-(3-carboxyphenyl)hydrazin-1-ylidene]-2-o...)
Affinity DataIC50: 3.82E+4nMAssay Description:PTP activity was measured in a black 96-well plate. Reaction was initiated by addition of the substrate DiFMUP to enzyme mixtures containing test com...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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