Compile Data Set for Download or QSAR
Report error Found 142 Enz. Inhib. hit(s) with all data for entry = 50026542
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  0.290nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  0.390nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  0.720nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.40nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50185473(4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....)
Affinity DataKi:  1.60nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human cloned muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  1.80nMAssay Description:Binding affinity to human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  2.20nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50262881(1-(4-fluorophenyl)-4-(3-hydroxy-3-phenyl-8-aza-bic...)
Affinity DataKi:  2.30nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  2.5nMAssay Description:Binding affinity to human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  2.80nMAssay Description:Binding affinity to human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  3.10nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  3.30nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity to human cloned muscarinic M1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50185473(4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....)
Affinity DataKi:  5.30nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50002334(CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...)
Affinity DataKi:  6.53nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50262929(4-[4-(4-Chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluo...)
Affinity DataKi:  6.60nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  7.20nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50095890(2-[2-(4-dibenzo[b,f][1,4]thiazepin-11-ylpiperazin-...)
Affinity DataKi:  8.70nMAssay Description:Binding affinity to human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  8.90nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  9.60nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  10nMAssay Description:Binding affinity to human cloned 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  10nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  10nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  11nMAssay Description:Binding affinity to human cloned 5HT6 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50262881(1-(4-fluorophenyl)-4-(3-hydroxy-3-phenyl-8-aza-bic...)
Affinity DataKi:  12.3nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  17nMAssay Description:Binding affinity to human cloned 5HT2C receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50155520(CHEMBL558392 | CHEMBL476935 | 4-[4-(4-Chloro-pheny...)
Affinity DataKi:  17.5nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  19nMAssay Description:Binding affinity to human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50262881(1-(4-fluorophenyl)-4-(3-hydroxy-3-phenyl-8-aza-bic...)
Affinity DataKi:  19.2nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  20nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50002334(CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...)
Affinity DataKi:  22nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50262929(4-[4-(4-Chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluo...)
Affinity DataKi:  23.6nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50185473(4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....)
Affinity DataKi:  27.7nMAssay Description:Binding affinity to human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50002334(CHEMBL140872 | 4-[4-(2-Pyrimidine)piperazin-1-yl]-...)
Affinity DataKi:  30.5nMAssay Description:Binding affinity to human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50185473(4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2....)
Affinity DataKi:  30.9nMAssay Description:Binding affinity to human cloned 5HT2A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  32nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50262881(1-(4-fluorophenyl)-4-(3-hydroxy-3-phenyl-8-aza-bic...)
Affinity DataKi:  37.6nMAssay Description:Binding affinity to human cloned 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50262930(4-(3-(4-chlorophenyl)-3,9-diazabicyclo[4.2.1]nonan...)
Affinity DataKi:  41.8nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(2) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50262929(4-[4-(4-Chlorophenyl)-1,4-diazepan-1-yl]-1-(4-fluo...)
Affinity DataKi:  43.3nMAssay Description:Binding affinity to human cloned dopamine D2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(3) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  45nMAssay Description:Binding affinity to human cloned dopamine D3 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  47nMAssay Description:Binding affinity to human cloned histamine H1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTransporter(Rat)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  48nMAssay Description:Binding affinity to rat NETMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  50nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(1A) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM35254(CHEMBL715 | 2-methyl-4-(4-methylpiperazin-1-yl)-10...)
Affinity DataKi:  52nMAssay Description:Binding affinity to human cloned dopamine D1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50048803(5-[2-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-et...)
Affinity DataKi:  53nMAssay Description:Binding affinity to human SERTMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetD(4) dopamine receptor(Human)
Florida A&M University

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  54nMAssay Description:Binding affinity to human cloned dopamine D4 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 142 total ) | Next | Last >>
Jump to: