Compile Data Set for Download or QSAR
Report error Found 33 Enz. Inhib. hit(s) with all data for entry = 2758
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24303((2-methoxy-4-{[3-methoxy-4-(sulfamoyloxy)phenyl](1...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24300((3-{[3-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24302((2-methoxy-5-{[4-methoxy-3-(sulfamoyloxy)phenyl](1...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24303((2-methoxy-4-{[3-methoxy-4-(sulfamoyloxy)phenyl](1...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24302((2-methoxy-5-{[4-methoxy-3-(sulfamoyloxy)phenyl](1...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24304({4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]p...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24317(4-[(R)-(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-...)
Affinity DataIC50: 0.600nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM13061(CHEMBL1444 | 4-[(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 0.890nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50: 1.5nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24316(4-[(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 1.80nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24306({2-bromo-4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)...)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24307({2-bromo-4-[(R)-(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 3.20nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24318(4-[(S)-(3-bromo-4-hydroxyphenyl)(1H-1,2,4-triazol-...)
Affinity DataIC50: 3.40nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24315(4-[(3-chloro-4-hydroxyphenyl)(1H-1,2,4-triazol-1-y...)
Affinity DataIC50: 5.5nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24314(4-[(4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]...)
Affinity DataIC50: 7.20nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24311(2-bromo-4-[(3-bromo-4-hydroxyphenyl)(1H-1,2,4-tria...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24305({2-chloro-4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 12nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24304({4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)methyl]p...)
Affinity DataIC50: 13nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24308({2-bromo-4-[(S)-(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 14.3nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24301((2-bromo-4-{[3-bromo-4-(sulfamoyloxy)phenyl](1H-1,...)
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24300((3-{[3-(sulfamoyloxy)phenyl](1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 99nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24312(5-[(3-hydroxy-4-methoxyphenyl)(1H-1,2,4-triazol-1-...)
Affinity DataIC50: 169nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24310(4-[(4-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]...)
Affinity DataIC50: 178nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24313(4-[(4-hydroxy-3-methoxyphenyl)(1H-1,2,4-triazol-1-...)
Affinity DataIC50: 215nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM13058(6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24301((2-bromo-4-{[3-bromo-4-(sulfamoyloxy)phenyl](1H-1,...)
Affinity DataIC50: 476nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24308({2-bromo-4-[(S)-(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 553nMAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24305({2-chloro-4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl...)
Affinity DataIC50: 920nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM24309(3-[(3-hydroxyphenyl)(1H-1,2,4-triazol-1-yl)methyl]...)
Affinity DataIC50: 2.46E+3nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24306({2-bromo-4-[(4-cyanophenyl)(1H-1,2,4-triazol-1-yl)...)
Affinity DataIC50: 2.60E+3nMAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetAromatase(Human)
University of Bath

LigandPNGBDBM13062(JMC514226 Compound 3 | (4-{[4-(sulfamoyloxy)phenyl...)
Affinity DataIC50: 3.04E+3nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM24307({2-bromo-4-[(R)-(4-cyanophenyl)(1H-1,2,4-triazol-1...)
Affinity DataIC50: 4.63E+3nMAssay Description:The extent of in vitro inhibition of aromatase activities was assessed using intact monolayers of JEG-3 cells. Aromatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed
TargetSteryl-sulfatase(Human)
University of Bath

LigandPNGBDBM13062(JMC514226 Compound 3 | (4-{[4-(sulfamoyloxy)phenyl...)
Affinity DataIC50: 1.00E+4nMpH: 7.5 T: 2°CAssay Description:The extent of in vitro inhibition of sulfatase activities was assessed using intact monolayers of JEG-3 cells. Sulfatase activity was measured using ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2008
Entry Details Article
PubMed