Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50026329
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50243848(2-((1-hydroxy-6-oxo-1,6-dihydropyridin-3-yl)ethyny...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of lipoxygenase-5 in human ED273b-BT cells assessed as amount of cysteinyl leukotriene secreted after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50243739(3-((1-hydroxy-6-oxo-1,6-dihydropyridin-3-yl)ethyny...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of lipoxygenase-5 in human ED273b-BT cells assessed as amount of cysteinyl leukotriene secreted after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM32020(LOX inhibitor, N/A | 4-[4-(3,4-dihydroxyphenyl)-2,...)
Affinity DataIC50: 3.50E+4nMAssay Description:Inhibition of lipoxygenase-5 in human ED273b-BT cells assessed as amount of cysteinyl leukotriene secreted after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Alberta

Curated by ChEMBL
LigandPNGBDBM50243740(1-(4-Benzenesulfonamido)-2-[5-(N-hydroxypyridin-2(...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition of lipoxygenase-5 in human ED273b-BT cells assessed as amount of cysteinyl leukotriene secreted after 24 hrs by immunoassayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed