Compile Data Set for Download or QSAR
Report error Found 149 Enz. Inhib. hit(s) with all data for entry = 50026258
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244215(2-(4-ethoxybenzyl)-1-(2-(dimethylamino)ethyl)-N,N-...)
Affinity DataEC50:  38nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244214(N-(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-1H-ben...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244181(1-(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-1H-ben...)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244180(1-(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-1H-ben...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244179(1-(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-1H-ben...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244178(N-(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-1H-ben...)
Affinity DataEC50:  2.60nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244140(N-(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-1H-ben...)
Affinity DataEC50:  2.70nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244099(1-(cyclopropylmethyl)-2-((5-ethoxypyridin-2-yl)met...)
Affinity DataEC50:  22nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244098(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-N,N-bis(2...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244097(2-(4-ethoxybenzyl)-N-cyclohexyl-1-(cyclopropylmeth...)
Affinity DataEC50:  4.20nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244096((2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-1H-benzo...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244061((2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-1H-benzo...)
Affinity DataEC50:  6.20nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244060(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-N,N-dipro...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244059(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-N-methyl-...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244057(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-N-ethyl-1...)
Affinity DataEC50:  52nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244010(2-(4-phenoxybenzyl)-N,N-diethyl-1-isopentyl-1H-ben...)
Affinity DataEC50:  3.20nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244009(2-(4-(cyclopropylmethoxy)benzyl)-N,N-diethyl-1-iso...)
Affinity DataEC50:  43nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244008(2-(4-(2,2,2-trifluoroethoxy)benzyl)-N,N-diethyl-1-...)
Affinity DataEC50:  65nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244007(2-(4-(trifluoromethoxy)benzyl)-N,N-diethyl-1-isope...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243963(2-(4-(cyclopentyloxy)benzyl)-N,N-diethyl-1-isopent...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243962(2-(4-cyclobutoxybenzyl)-N,N-diethyl-1-isopentyl-1H...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243961(2-(4-isopropoxybenzyl)-N,N-diethyl-1-isopentyl-1H-...)
Affinity DataEC50:  2.40nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243913(2-(4-methoxybenzyl)-N,N-diethyl-1-isopentyl-1H-ben...)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243911(2-((4-ethoxyphenyl)(hydroxy)methyl)-N,N-diethyl-1-...)
Affinity DataEC50:  69nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243910(2-(4-ethoxybenzoyl)-N,N-diethyl-1-isopentyl-1H-ben...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243862((S)-2-(4-ethoxybenzyl)-N,N-diethyl-1-((1-methylpyr...)
Affinity DataEC50:  3.40nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243861((R)-2-(4-ethoxybenzyl)-N,N-diethyl-1-((1-methylpip...)
Affinity DataEC50:  2.30nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243860((R)-2-(4-ethoxybenzyl)-N,N-diethyl-1-(piperidin-2-...)
Affinity DataEC50:  13nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243859((S)-2-(4-ethoxybenzyl)-N,N-diethyl-1-(piperidin-2-...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243708((R)-2-(4-ethoxybenzyl)-N,N-diethyl-1-((tetrahydrof...)
Affinity DataEC50:  8.30nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244276(2-(4-ethoxybenzyl)-N,N-diethyl-1-isopentyl-1H-benz...)
Affinity DataEC50:  2.90nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243707((S)-2-(4-ethoxybenzyl)-N,N-diethyl-1-((tetrahydrof...)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243706(2-(4-ethoxybenzyl)-N,N-diethyl-1-((tetrahydro-2H-p...)
Affinity DataEC50:  1nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50243705(2-(4-ethoxybenzyl)-N,N-diethyl-1-(furan-2-ylmethyl...)
Affinity DataEC50:  3.30nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244353(2-(4-ethoxybenzyl)-N,N-diethyl-1-(pyridin-4-ylmeth...)
Affinity DataEC50:  5nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244352(2-(4-ethoxybenzyl)-N,N-diethyl-1-(pyridin-2-ylmeth...)
Affinity DataEC50:  25nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244351(2-(4-ethoxybenzyl)-1-benzyl-N,N-diethyl-1H-benzo[d...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244319(1-adamantan-1-ylmethyl-2-(4-ethoxy-benzyl)-1H-benz...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244318(2-(4-ethoxybenzyl)-1-(cyclohexylmethyl)-N,N-diethy...)
Affinity DataEC50:  0.520nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244317(2-(4-ethoxybenzyl)-1-(cyclopentylmethyl)-N,N-dieth...)
Affinity DataEC50:  0.700nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244316(2-(4-ethoxybenzyl)-1-(cyclobutylmethyl)-N,N-diethy...)
Affinity DataEC50:  1.30nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244277(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-N,N-dieth...)
Affinity DataEC50:  2.10nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataEC50:  1.5nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at cloned human CB2 receptor in Sf9 cells assessed as stimulation of [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244317(2-(4-ethoxybenzyl)-1-(cyclopentylmethyl)-N,N-dieth...)
Affinity DataKi:  1nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244316(2-(4-ethoxybenzyl)-1-(cyclobutylmethyl)-N,N-diethy...)
Affinity DataKi:  1.60nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244060(2-(4-ethoxybenzyl)-1-(cyclopropylmethyl)-N,N-dipro...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244319(1-adamantan-1-ylmethyl-2-(4-ethoxy-benzyl)-1H-benz...)
Affinity DataKi:  2.80nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM60994((10R,10aR)-6,6,9-Trimethyl-3-pentyl-6a,7,8,10a-tet...)
Affinity DataKi:  2.90nMAssay Description:Displacement of [3H]CP-55940 from human CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Astrazeneca R&D MontréAl

Curated by ChEMBL
LigandPNGBDBM50244318(2-(4-ethoxybenzyl)-1-(cyclohexylmethyl)-N,N-diethy...)
Affinity DataKi:  3.70nMAssay Description:Displacement of [3H]CP-55940 from human CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 149 total ) | Next | Last >>
Jump to: