Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 50026214
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271179(2-(2-(quinolin-2-yl)vinyl)phenol | CHEMBL487942 | ...)
Affinity DataIC50: 4.63E+3nMAssay Description:Reduction of recombinant ECE2 activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271178(1-(pyrrolidin-1-yl)-2-(quinoxalin-6-yl)ethanone | ...)
Affinity DataIC50: 5.83E+3nMAssay Description:Reduction of recombinant ECE2 activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50001270(CHEMBL127545 | 2-(2-(quinolin-2-yl)vinyl)phenol | ...)
Affinity DataIC50: 6.42E+3nMAssay Description:Reduction of recombinant ECE2 activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271180(2-(2-hydroxy-3-methoxystyryl)quinolin-8-ol | CHEMB...)
Affinity DataIC50: 3.29E+4nMAssay Description:Reduction of recombinant ECE2 activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetEEF1AKMT4-ECE2 readthrough transcript protein(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271181(cid_5731702 | CHEMBL488140 | 2-(3-methoxystyryl)qu...)
Affinity DataIC50: 3.57E+4nMAssay Description:Reduction of recombinant ECE2 activity measured by McaBk2 fluorescent substrate hydrolysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeprilysin(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50271178(1-(pyrrolidin-1-yl)-2-(quinoxalin-6-yl)ethanone | ...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of NeprilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetNeprilysin(Human)
Mount Sinai School of Medicine

Curated by ChEMBL
LigandPNGBDBM50001270(CHEMBL127545 | 2-(2-(quinolin-2-yl)vinyl)phenol | ...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of NeprilysinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed