Compile Data Set for Download or QSAR
Report error Found 11 Enz. Inhib. hit(s) with all data for entry = 50026185
TargetMu-type opioid receptor(Human)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radioligand from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of radioligand from mu opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataIC50: 1.00E+4nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2.20nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267352((-)-[(2R)-(1,4-Dibenzyl)-1,4-diazepan-2-yl]methano...)
Affinity DataKi:  7.40nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267386((R)-(1,4-dibenzylpiperazin-2-yl)methanol | CHEMBL4...)
Affinity DataKi:  38nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM81982(CAS_97-39-2 | cid_7333 | Di-o-tolylguanidine | DIT...)
Affinity DataKi:  164nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50002238(1-(4-fluorophenyl)-4-(4-(5-fluoropyrimidin-2-yl)pi...)
Affinity DataKi:  265nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267353((-)-[(2R)-1-Benzyl-4-(2,2-dimethoxyethyl)-1,4-diaz...)
Affinity DataKi:  320nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
Institut FüR Pharmazeutische Und Medizinische Chemie

Curated by ChEMBL
LigandPNGBDBM50267387((R)-(1-benzyl-4-(2,2-dimethoxyethyl)piperazin-2-yl...)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain membrane by liquid scintillation analyzerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed