Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50038236
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373451(CHEMBL411295)
Affinity DataIC50: 7nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373441(CHEMBL410646)
Affinity DataIC50: 16nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373449(CHEMBL261362)
Affinity DataIC50: 27nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373456(CHEMBL261108)
Affinity DataIC50: 45nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373450(CHEMBL261418)
Affinity DataIC50: 60nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373443(CHEMBL259051)
Affinity DataIC50: 90nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50239833((3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphos...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142317((2-bromo-4-(3-oxo-2,3-diphenylpropyl)phenyl)difluo...)
Affinity DataIC50: 120nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373457(CHEMBL261419)
Affinity DataIC50: 160nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373447(CHEMBL260914)
Affinity DataIC50: 250nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373442(CHEMBL260442)
Affinity DataIC50: 310nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373446(CHEMBL408382)
Affinity DataIC50: 330nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373454(CHEMBL259050)
Affinity DataIC50: 510nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373448(CHEMBL407893)
Affinity DataIC50: 1.26E+3nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373444(CHEMBL259267)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373445(CHEMBL259266)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142314({Difluoro-[4-(3-oxo-2,3-diphenyl-propyl)-phenyl]-m...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373452(CHEMBL405419)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373443(CHEMBL259051)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373451(CHEMBL411295)
Affinity DataIC50: 3.78E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373457(CHEMBL261419)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373456(CHEMBL261108)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373446(CHEMBL408382)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142314({Difluoro-[4-(3-oxo-2,3-diphenyl-propyl)-phenyl]-m...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373441(CHEMBL410646)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50142317((2-bromo-4-(3-oxo-2,3-diphenylpropyl)phenyl)difluo...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373453(CHEMBL260210)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373452(CHEMBL405419)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373450(CHEMBL261418)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373449(CHEMBL261362)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373448(CHEMBL407893)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373447(CHEMBL260914)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373445(CHEMBL259266)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373444(CHEMBL259267)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373454(CHEMBL259050)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50239833((3-bromo-7-cyanonaphthalen-2-yl)difluoromethylphos...)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetReceptor-type tyrosine-protein phosphatase C(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373442(CHEMBL260442)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of CD45 by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373453(CHEMBL260210)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Merck Frosst Centre For Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM50373455(CHEMBL261107)
Affinity DataKi:  1.79E+5nMAssay Description:Inhibition of PTP1B by fluorescein diphosphate assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2012
Entry Details Article
PubMed