Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50026097
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271572(1-[4-Chlorophenylcarbonyl]-4-[4-(pyridin-4-yl)phen...)
Affinity DataIC50: 3nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271622(1-[4-Chlorophenylsulfonyl]-4-[4-(4-methylpiperazin...)
Affinity DataIC50: 6nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271571(1-[4-Chlorophenylsulfonyl]-4-[4-(pyridin-4-yl)phen...)
Affinity DataIC50: 13nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271621(1-[4-(Trifluoromethoxy)phenylcarbonyl]-4-[4-(dimet...)
Affinity DataIC50: 20nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271529(N-[2-(4-(4-Dimethylaminomethylphenyl)phenyl)ethyl]...)
Affinity DataIC50: 28nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271623(1-[4-Chlorophenylcarbonyl]-4-[4-(imidazol-1-yl)phe...)
Affinity DataIC50: 32nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271620(1-[4-Chlorophenylsulfonyl]-4-[4-(dimethylaminometh...)
Affinity DataIC50: 32nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271619(1-[4-Chlorophenylcarbonyl]-4-[4-(dimethylaminometh...)
Affinity DataIC50: 40nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271530(N-[2-(4-(4-((Pyrolidin-1-yl)methyl)phenyl)phenyl)e...)
Affinity DataIC50: 63nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271528(rac-N-(4-(hydroxy(phenyl)methyl)phenethyl)-4-cyano...)
Affinity DataEC50:  100nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271573(1-[4-Chlorobenzyl]-4-[4-(pyridin-4-yl)phenylmethyl...)
Affinity DataIC50: 316nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271570(1-[4-Chlorophenylsulfonyl]-4-[3-(pyridin-4-yl)phen...)
Affinity DataIC50: 500nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetLanosterol synthase(Human)
Laboratoire Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50271574(1-[4-Methoxyphenylcarbonyl]-4-[4-(pyridin-4-yl)phe...)
Affinity DataIC50: 2.51E+3nMAssay Description:Inhibition of 2,3-oxidosqualene-lanosterol cyclaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed