Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50038225
TargetMitogen-activated protein kinase 8(Rat)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of JNK1 in rat H9c2 cells assessed as inhibition of anisomycin-induced AP1 phosphorylation after 30 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373218(CHEMBL260429)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373200(CHEMBL261014)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373202(CHEMBL261841)
Affinity DataIC50: 12nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373205(CHEMBL259916)
Affinity DataIC50: 14nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373204(CHEMBL259706)
Affinity DataIC50: 20nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373193(CHEMBL259092)
Affinity DataIC50: 21nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373195(CHEMBL259812)
Affinity DataIC50: 28nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 10(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 30nMAssay Description:Inhibition of JNK3More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 30nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 34nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373206(CHEMBL410707)
Affinity DataIC50: 42nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373203(CHEMBL407956)
Affinity DataIC50: 43nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373201(CHEMBL261186)
Affinity DataIC50: 48nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373216(CHEMBL259404)
Affinity DataIC50: 59nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373217(CHEMBL411635)
Affinity DataIC50: 61nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373194(CHEMBL258883)
Affinity DataIC50: 63nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373207(CHEMBL258703)
Affinity DataIC50: 79nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373212(CHEMBL258676)
Affinity DataIC50: 86nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373219(CHEMBL260126)
Affinity DataIC50: 89nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373199(CHEMBL410318)
Affinity DataIC50: 95nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373208(CHEMBL409936)
Affinity DataIC50: 100nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM16018(cid_8515 | SP 600125 | ChemBiol10705 Compound 4 | ...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373197(CHEMBL408224)
Affinity DataIC50: 140nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50169959([3H-Benzothiazol-(2Z)-ylidene]-[2-(2-pyridin-3-yl-...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373213(CHEMBL409429)
Affinity DataIC50: 190nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373211(CHEMBL259934)
Affinity DataIC50: 450nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373214(CHEMBL259544)
Affinity DataIC50: 860nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373209(CHEMBL258457)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373211(CHEMBL259934)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373213(CHEMBL409429)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373211(CHEMBL259934)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373209(CHEMBL258457)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373214(CHEMBL259544)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373212(CHEMBL258676)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373209(CHEMBL258457)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373214(CHEMBL259544)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373212(CHEMBL258676)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373213(CHEMBL409429)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373210(CHEMBL406971)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373210(CHEMBL406971)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373210(CHEMBL406971)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373198(CHEMBL261086)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 8(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373196(CHEMBL259406)
Affinity DataIC50: 8.80E+3nMAssay Description:Inhibition of human JNK1 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 1(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of MEKKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of p38 alphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein kinase C theta type(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PKCthetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of TAK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetInhibitor of nuclear factor kappa-B kinase subunit beta(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of IKK-betaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase 3(Human)
Takeda Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50373215(CHEMBL259060)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of ERK1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed