Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 4618
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50: 1.60E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 3.30E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81327(Tetrahydroquinoxalin analog, J)
Affinity DataIC50: 5.90E+3nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5-monophosphate dehydrogenase(Cryptosporidium parvum)
Brandeis University

LigandPNGBDBM81329(N-[(Z)-N-(pyridin-3-yl)carboximidoyl]-2,3-dihydro-...)
Affinity DataIC50: 1.90E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50: 2.50E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Brandeis University

LigandPNGBDBM81328(methyl 3-methyl-2-oxo-1,2-dihydroquinoline-4-carbo...)
Affinity DataIC50: 2.50E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Brandeis University

LigandPNGBDBM50294184(CHEMBL561640 | N-(4-chlorophenyl)-2-phenoxypropana...)
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

LigandPNGBDBM81327(Tetrahydroquinoxalin analog, J)
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Brandeis University

LigandPNGBDBM81327(Tetrahydroquinoxalin analog, J)
Affinity DataIC50: 5.00E+4nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 1(Human)
Brandeis University

LigandPNGBDBM81329(N-[(Z)-N-(pyridin-3-yl)carboximidoyl]-2,3-dihydro-...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed
TargetInosine-5'-monophosphate dehydrogenase 2(Human)
Brandeis University

LigandPNGBDBM81329(N-[(Z)-N-(pyridin-3-yl)carboximidoyl]-2,3-dihydro-...)
Affinity DataIC50: 5.00E+5nMpH: 8.0 T: 2°CAssay Description:Enzyme inhibition assay using recombinant human IMPDH1 and IMPDH2 and C.parvum were expressed in guaB strains of escherichia coli.More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/9/2011
Entry Details Article
PubMed