Compile Data Set for Download or QSAR
Report error Found 48 Enz. Inhib. hit(s) with all data for entry = 3056
LigandPNGBDBM27391(5,13,17-triazatetracyclo[8.7.0.0^{2,7}.0^{11,16}]h...)
Affinity DataIC50: 2nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27413(2-(2-aminopyrimidin-4-yl)-1-(2-fluoroethyl)-1H,4H,...)
Affinity DataIC50: 3nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27412(2-(2-aminopyrimidin-4-yl)-1-(cyclopropylmethyl)-1H...)
Affinity DataIC50: 4nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27390(2-(2-amino-5-bromopyrimidin-4-yl)-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 4nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27406(2-(2-aminopyrimidin-4-yl)-1-(2,2,2-trifluoroethyl)...)
Affinity DataIC50: 5nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27351(2-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...)
Affinity DataIC50: 7nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27421(2-[2-(phenylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 7nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27404(2-(2-aminopyrimidin-4-yl)-1-ethyl-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 8nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27382(2-(3-fluoropyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,...)
Affinity DataIC50: 9nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27344(JMC502647 Compound 8 | 2-(pyridin-4-yl)-1H,4H,5H,6...)
Affinity DataIC50: 10nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27407(2-(2-aminopyrimidin-4-yl)-1-propyl-1H,4H,5H,6H,7H-...)
Affinity DataIC50: 12nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27411(2-(2-aminopyrimidin-4-yl)-1-(2-methylpropyl)-1H,4H...)
Affinity DataIC50: 13nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27409(2-(2-aminopyrimidin-4-yl)-1-cyclobutyl-1H,4H,5H,6H...)
Affinity DataIC50: 14nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27384(2-{1H-pyrrolo[2,3-b]pyridin-4-yl}-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 14nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27383(2-(pyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]py...)
Affinity DataIC50: 20nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27410(2-(2-aminopyrimidin-4-yl)-1-butyl-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 23nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27397(2-(pyridin-4-yl)-1H,4H,5H,6H-pyrrolo[2,3-c]pyrrol-...)
Affinity DataIC50: 27nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27389(2-(2-aminopyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2...)
Affinity DataIC50: 28nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27408(2-(2-aminopyrimidin-4-yl)-1-(propan-2-yl)-1H,4H,5H...)
Affinity DataIC50: 42nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27393(3-methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...)
Affinity DataIC50: 45nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27414(2-(2-aminopyrimidin-4-yl)-1-(4,4,4-trifluorobutyl)...)
Affinity DataIC50: 47nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27400(1-ethyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,...)
Affinity DataIC50: 67nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27403(2-(2-aminopyrimidin-4-yl)-1-methyl-1H,4H,5H,6H,7H-...)
Affinity DataIC50: 88nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27418(2-(2-aminopyrimidin-4-yl)-1-(1-methylpiperidin-4-y...)
Affinity DataIC50: 120nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27405(2-(2-aminopyrimidin-4-yl)-1-(2-hydroxyethyl)-1H,4H...)
Affinity DataIC50: 138nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27388(JMC502647 Compound 7 | 2-(2-chloropyridin-4-yl)-1H...)
Affinity DataIC50: 147nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27398(2-(pyridin-4-yl)-1H,4H,5H,6H,7H,8H-pyrrolo[3,2-c]a...)
Affinity DataIC50: 158nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27402(2-(pyridin-4-yl)-1-(2,2,2-trifluoroethyl)-1H,4H,5H...)
Affinity DataIC50: 160nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27385(2-(9H-purin-6-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyr...)
Affinity DataIC50: 178nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27396(2-(pyridin-4-yl)-4H,5H,6H,7H-furo[3,2-c]pyridin-4-...)
Affinity DataIC50: 201nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27395(2-(pyridin-4-yl)-4H,5H,6H,7H-pyrazolo[1,5-a]pyrazi...)
Affinity DataIC50: 210nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27422(2-[2-(benzylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 220nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27419(2-[2-(propylamino)pyrimidin-4-yl]-1H,4H,5H,6H,7H-p...)
Affinity DataIC50: 259nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27426(N-(4-{4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-2...)
Affinity DataIC50: 262nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27417(2-(2-aminopyrimidin-4-yl)-1-benzyl-1H,4H,5H,6H,7H-...)
Affinity DataIC50: 290nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27424(N-(4-{4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-2...)
Affinity DataIC50: 323nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27394(1-methyl-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...)
Affinity DataIC50: 404nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27420(2-{2-[(2-methylpropyl)amino]pyrimidin-4-yl}-1H,4H,...)
Affinity DataIC50: 636nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27423(2-{2-[(cyclohexylmethyl)amino]pyrimidin-4-yl}-1H,4...)
Affinity DataIC50: 655nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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PubMed
LigandPNGBDBM27399(4-oxo-2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-...)
Affinity DataIC50: 863nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27425(2-methyl-N-(4-{4-oxo-1H,4H,5H,6H,7H-pyrrolo[3,2-c]...)
Affinity DataIC50: 1.40E+3nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27401(1-(2-hydroxyethyl)-2-(pyridin-4-yl)-1H,4H,5H,6H,7H...)
Affinity DataIC50: 3.30E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27415(2-(2-aminopyrimidin-4-yl)-1-cyclohexyl-1H,4H,5H,6H...)
Affinity DataIC50: 5.00E+3nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27416(2-(2-aminopyrimidin-4-yl)-1-phenyl-1H,4H,5H,6H,7H-...)
Affinity DataIC50: 5.00E+3nMAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27392(3-(2-aminopyrimidin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3...)
Affinity DataIC50: 5.00E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27387(1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-one | pyrro...)
Affinity DataIC50: 5.00E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27386(2-phenyl-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyridin-4-on...)
Affinity DataIC50: 5.00E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
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LigandPNGBDBM27381(2-(pyridin-3-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)
Affinity DataIC50: 5.00E+3nMpH: 7.9 T: 2°CAssay Description:The potency of the compound toward kinase activity was determined using a Dowex resin-based assay. The substrate was phosphorylated by kinase in the ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed