Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 2453
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20722((1R,2R)-2-({4-[4-({[2-fluoro-5-(trifluoromethyl)ph...)
Affinity DataIC50: 5nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20721((1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino...)
Affinity DataIC50: 6nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20716((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20727((1R,2R)-2-[(4-{4-[(2H-1,3-benzodioxol-5-ylcarbamoy...)
Affinity DataIC50: 7nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20718((1R,2R)-2-({4-[4-({[2-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20724((1R,2R)-2-{[4-(4-{[(4-methoxyphenyl)carbamoyl]amin...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20726((1R,2R)-2-({4-[4-({[4-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50: 9nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20719((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50: 10nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20720((1R,2R)-2-{[4-(4-{[(3-fluorophenyl)carbamoyl]amino...)
Affinity DataIC50: 11nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20726((1R,2R)-2-({4-[4-({[4-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50: 14nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20718((1R,2R)-2-({4-[4-({[2-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50: 16nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20719((1R,2R)-2-({4-[4-({[3-(trifluoromethyl)phenyl]carb...)
Affinity DataIC50: 17nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20721((1R,2R)-2-{[4-(4-{[(3-chlorophenyl)carbamoyl]amino...)
Affinity DataIC50: 19nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20722((1R,2R)-2-({4-[4-({[2-fluoro-5-(trifluoromethyl)ph...)
Affinity DataIC50: 21nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20716((1R,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50: 24nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20724((1R,2R)-2-{[4-(4-{[(4-methoxyphenyl)carbamoyl]amin...)
Affinity DataIC50: 28nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20725((1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}...)
Affinity DataIC50: 35nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20720((1R,2R)-2-{[4-(4-{[(3-fluorophenyl)carbamoyl]amino...)
Affinity DataIC50: 39nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20727((1R,2R)-2-[(4-{4-[(2H-1,3-benzodioxol-5-ylcarbamoy...)
Affinity DataIC50: 63nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20730((1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1...)
Affinity DataIC50: 73nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20728((1S,2S)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50: 96nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20729((1S,2R)-2-[(4-{4-[(phenylcarbamoyl)amino]phenyl}ph...)
Affinity DataIC50: 98nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20730((1R,2R)-2-{[4-(3-fluoro-4-{[6-(trifluoromethoxy)-1...)
Affinity DataIC50: 207nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Mouse)
Abbott Laboratories

LigandPNGBDBM20725((1R,2R)-2-{[4-(4-{[(4-cyanophenyl)carbamoyl]amino}...)
Affinity DataIC50: 603nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
Abbott Laboratories

LigandPNGBDBM20723((1R,2R)-2-({4-[4-({[3-(methylcarbamoyl)phenyl]carb...)
Affinity DataIC50: 994nMpH: 7.5 T: 2°CAssay Description:DGAT-1 activity was characterized by catalyzing the transfer of the radiolabeled decanoyl group onto the syn-3 position of didecanoyl glycerol. The r...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2008
Entry Details Article
PubMed