Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50003952
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477968(CHEMBL256616)
Affinity DataIC50: 23nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477982(CHEMBL403372)
Affinity DataIC50: 62nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50157973(5-chloro-thiophene-2-sulfonic acid tricyclo[8.2.1....)
Affinity DataIC50: 63nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477979(CHEMBL402285)
Affinity DataIC50: 81nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477981(CHEMBL256384)
Affinity DataIC50: 105nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477973(CHEMBL255740)
Affinity DataIC50: 212nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477978(CHEMBL257231)
Affinity DataIC50: 257nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477972(CHEMBL258136)
Affinity DataIC50: 416nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477969(CHEMBL273144)
Affinity DataIC50: 491nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477970(CHEMBL269999)
Affinity DataIC50: 685nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477971(CHEMBL404092)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477974(CHEMBL255767)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477975(CHEMBL272927)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477976(CHEMBL437972)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477977(CHEMBL257230)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetPresenilin-1(Human)
Merck Sharp and Dohme Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50477980(CHEMBL272926)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human gamma secretase in human SHSY5Y cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed