Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 2985
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26611((hydrazinecarbonyl)-N-(pyrimidin-2-yl)methanesulfo...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26612(2,3-dinitro-9H-fluoren-9-one | Compound 133896)
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26614(2-[(4-hydroxy-3-methylphenyl)[(1Z)-3-methyl-4-oxoc...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26615(8-(8-carboxynaphthalen-1-yl)naphthalene-1-carboxyl...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26616(2-aminobenzene-1,3,5-trisulfonamide | Compound 258...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26617(4-[(2-carboxyphenyl)carbonyl]benzene-1,2-dicarboxy...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26619(2,2,2,5-tetrahydroxy-1,3,2-dioxastibinane-4,6-dica...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26620(4-amino-5-{[(4-methylbenzene)sulfonyl]oxy}naphthal...)
Affinity DatapH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26613((2E)-3-{3-[dihydroxy(oxo)--stibanyl]phenyl}prop-2-...)
Affinity DataIC50: 200nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26618(N-{4-[dihydroxy(oxo)--stibanyl]phenyl}benzamide | ...)
Affinity DataIC50: 300nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26621(4-[dihydroxy(oxo)--stibanyl]-2-nitrobenzoic acid |...)
Affinity DataKi:  19nM ΔG°:  -43.6kJ/mole IC50: 4nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Human)
The Johns Hopkins University

LigandPNGBDBM26622(ethyl 4-{4-[dihydroxy(oxo)--stibanyl]phenyl}butano...)
Affinity DataKi:  36nM ΔG°:  -42.1kJ/mole IC50: 17nMpH: 7.5 T: 2°CAssay Description:The screening assay was performed using 384-well microtiter plate first spotted with test compounds. Then Ape1 in reaction buffer was added to each w...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/30/2009
Entry Details Article
PubMed