Compile Data Set for Download or QSAR
Report error Found 83 Enz. Inhib. hit(s) with all data for entry = 50021595
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226096(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226064(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226086((S)-1-((3R,4R)-1-(4-cyanobenzyl)-3-aminopyrrolidin...)
Affinity DataIC50: 2.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226093((1R)-2-((3R,4R)-1-(1-(4-(1H-1,2,4-triazol-1-yl)phe...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226077((3S,4S)-4-amino-3-(pyrrolidine-1-carbonyl)-1-(quin...)
Affinity DataIC50: 3nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226065((S)-1-((3R,4R)-1-(4-(1H-1,2,4-triazol-1-yl)benzyl)...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226067((S)-1-((3R,4R)-1-(4-(1-methyl-1H-pyrazol-5-yl)benz...)
Affinity DataIC50: 3.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226078(1-((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecarb...)
Affinity DataIC50: 3.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226074((1R)-2-((3R,4R)-3-amino-1-(chroman-4-yl)pyrrolidin...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226084((S)-1-((3R,4R)-1-(3-cyano-4-fluorobenzyl)-3-aminop...)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226076((1R)-2-((3R,4R)-1-(2-methyl-4-(1H-1,2,4-triazol-1-...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226102(4-(((3R,4R)-3-amino-4-((2R)-2-cyanocyclopentanecar...)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226066((S)-1-((3R,4R)-1-(4-(3-methyl-1H-1,2,4-triazol-1-y...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226092((1R,3S)-2-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-...)
Affinity DataIC50: 5.30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226075((S)-1-((3R,4R)-1-(4-(2H-1,2,3-triazol-2-yl)benzyl)...)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226088((S)-1-((3R,4R)-3-amino-1-(1-(4-cyanophenyl)ethyl)p...)
Affinity DataIC50: 5.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226080((S)-1-((3R,4R)-3-amino-1-(quinolin-3-ylmethyl)pyrr...)
Affinity DataIC50: 6.20nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226099((S)-1-((3R,4R)-1-(4-(1H-pyrazol-5-yl)benzyl)-3-ami...)
Affinity DataIC50: 6.70nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226071((S)-1-((3R,4R)-1-(4-(5-methyl-1,3,4-oxadiazol-2-yl...)
Affinity DataIC50: 8.5nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226073((S)-1-((3R,4R)-1-(4-(1-methyl-1H-pyrazol-4-yl)benz...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226069((S)-1-((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226079(((3R,4R)-4-amino-1-quinolin-3-ylmethyl-pyrrolidin-...)
Affinity DataIC50: 27nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226101([(3R,4R)-4-amino-1-(4-tetrazol-1-yl-benzoyl)-pyrro...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226082([(3R,4R)-4-amino-1-(quinoline-6-carbonyl)-pyrrolid...)
Affinity DataIC50: 38nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226083([(3R,4R)-4-amino-1-(4-[1,2,4]triazol-1-yl-benzoyl)...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226089([(3R,4R)-4-amino-1-(benzothiazole-6-carbonyl)-pyrr...)
Affinity DataIC50: 42nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226072((1R)-2-((3R,4R)-1-(3-methyl-4-(1H-1,2,4-triazol-1-...)
Affinity DataIC50: 46nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226070([(3R,4R)-4-amino-1-(isoquinoline-3-carbonyl)-pyrro...)
Affinity DataIC50: 47nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226100([(3R,4R)-4-amino-1-(quinoline-3-carbonyl)-pyrrolid...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226098([(3R,4R)-4-amino-1-(4-tetrazol-1-yl-benzyl)-pyrrol...)
Affinity DataIC50: 50nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226097([(3R,4R)-4-amino-1-(benzo[b]thiophene-2-carbonyl)-...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226094((3R,4R)-4-amino-3-(pyrrolidine-1-carbonyl)-1-(quin...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226087([(3R,4R)-4-amino-1-(4-[1,2,4]triazol-1-yl-benzyl)-...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226095(5-(((3R,4R)-3-amino-4-(pyrrolidine-1-carbonyl)pyrr...)
Affinity DataIC50: 78nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226091([(3R,4R)-4-amino-1-(naphthalene-2-carbonyl)-pyrrol...)
Affinity DataIC50: 79nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226068(((3R,4R)-1-(3,4-difluorobenzyl)-4-aminopyrrolidin-...)
Affinity DataIC50: 80nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226081(4-(((3R,4R)-3-amino-4-(pyrrolidine-1-carbonyl)pyrr...)
Affinity DataIC50: 81nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226090(((3R,4R)-4-amino-1-(1-(4-nitrophenyl)ethyl)pyrroli...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226063([(3R,4R)-4-amino-1-(5-chloro-benzofuran-2-carbonyl...)
Affinity DataIC50: 86nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 4(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226085(((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)-4-ami...)
Affinity DataIC50: 91nMAssay Description:Inhibition of human DPP4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226085(((3R,4R)-1-(4-(1,2,3-thiadiazol-4-yl)benzyl)-4-ami...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226098([(3R,4R)-4-amino-1-(4-tetrazol-1-yl-benzyl)-pyrrol...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226090(((3R,4R)-4-amino-1-(1-(4-nitrophenyl)ethyl)pyrroli...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50226065((S)-1-((3R,4R)-1-(4-(1H-1,2,4-triazol-1-yl)benzyl)...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of hERG by patch clamp assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226081(4-(((3R,4R)-3-amino-4-(pyrrolidine-1-carbonyl)pyrr...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226068(((3R,4R)-1-(3,4-difluorobenzyl)-4-aminopyrrolidin-...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226095(5-(((3R,4R)-3-amino-4-(pyrrolidine-1-carbonyl)pyrr...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226063([(3R,4R)-4-amino-1-(5-chloro-benzofuran-2-carbonyl...)
Affinity DataIC50: 4.25E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226087([(3R,4R)-4-amino-1-(4-[1,2,4]triazol-1-yl-benzyl)-...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDipeptidyl peptidase 8(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50226079(((3R,4R)-4-amino-1-quinolin-3-ylmethyl-pyrrolidin-...)
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of human DPP8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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