Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50025593
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM24485(3-{4-[(6,7-dimethoxyquinolin-4-yl)oxy]-3-fluorophe...)
Affinity DataKi:  1nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50184869(N-{4-[(6,7-Dimethoxy-4-quinolyl)oxy]phenyl}-N'-(2-...)
Affinity DataKi:  2nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245264(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)oxy]pyridin-2-...)
Affinity DataKi:  3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245431(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)-oxy]pyridin-2...)
Affinity DataKi:  50nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245395(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)oxy]pyridin-2-...)
Affinity DataKi:  80nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245311(N-[5-(6,7-Dimethoxy-quinolin-4-yloxy)-pyridin-2-yl...)
Affinity DataKi:  400nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245394(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)oxy]pyridin-2-...)
Affinity DataKi:  500nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245393(N-[({5-[(6,7-Dimethoxyquinolin-4-yl)oxy]pyridin-2-...)
Affinity DataKi:  500nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245392(N-Benzyl-N0-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]py...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245351(N-{5-[(6,7-Dimethoxyquinolin-4-yl)amino]pyridin-2-...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245353(N-Cyclohexyl-N0-{5-[(6,7-dimethoxyquinolin-4-yl)ox...)
Affinity DataKi:  2.80E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245350(N-Cyclohexyl-N0-{5-[(6,7-dimethoxyquinolin-4-yl)ox...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245352(1-[5-(6,7-Dimethoxy-quinolin-4-yloxy)-pyridin-2-yl...)
Affinity DataKi:  6.40E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245310(N-{5-[(6,7-Dimethoxyquinolin-4-yl)oxy]-pyridin-2-y...)
Affinity DataKi:  7.00E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245312(N-{5-[(6,7-Dimethoxyquinolin-4-yl)-oxy]pyridin-2-y...)
Affinity DataKi:  8.00E+3nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed
TargetHepatocyte growth factor receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50245313(N-{5-[(6,7-dimethoxyquinolin-4-yl)oxy]-pyridin-2-y...)
Affinity DataKi: >3.00E+4nMAssay Description:Inhibition of human activated c-Met by PK/LDH coupled kinetic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMed