Compile Data Set for Download or QSAR
Report error Found 82 Enz. Inhib. hit(s) with all data for entry = 50038050
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224869((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224871((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224869((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224869((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  6.40nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224873((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  11nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224873((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  1.10nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224873((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  0.680nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50039029(CHEMBL13470 | 3-[(4-Allyl-2,5-dimethyl-piperazin-1...)
Affinity DataEC50:  4.80nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224867((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224871((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  24nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM21015([tyrosyl-3,5-3H(N)]-D-Ala2-Mephe4-glyol5-enkephali...)
Affinity DataEC50:  55nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224872((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  12nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  5.60nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224877((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50194264(cis-rac-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataEC50:  3nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50000296(CHEMBL441765 | CHEMBL482811 | U-50488H | US1149237...)
Affinity DataEC50:  36nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224877((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  20nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224872((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  18nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224867((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  42nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224877((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  14nMAssay Description:Agonist activity at human delta opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  4.60nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224872((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataEC50:  6.80nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cell membrane by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50194264(cis-rac-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataEC50:  4.40nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membrane by [35S]GTP-gamma-S binding assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224873((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataIC50: 24nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50194264(cis-rac-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataIC50: 150nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataIC50: 230nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224871((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataIC50: 320nMAssay Description:Antagonist activity at human mu opioid receptor expressed in CHO cell membrane assessed as inhibition of DAMGO induced [35S]GTP-gamma-S bindingMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50097579(8-CAC | CHEMBL58646 | (6S,11R)-3-Cyclopropylmethyl...)
Affinity DataKi:  0.0600nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.0630nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224873((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.0840nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224873((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224879((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224871((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.180nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224869((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224879((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.200nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224881((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.290nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50194264(cis-rac-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataKi:  0.300nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50097579(8-CAC | CHEMBL58646 | (6S,11R)-3-Cyclopropylmethyl...)
Affinity DataKi:  0.310nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224870((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.350nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224877((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.380nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224869((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.710nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224881((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.720nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50194264(cis-rac-3-Cyclopropylmethyl-6,11-dimethyl-1,2,3,4,...)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDelta-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224879((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]naltrindole from delta opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224872((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.950nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224868((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  0.980nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224868((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  1.10nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMu-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224874((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]DAMGO from mu opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKappa-type opioid receptor(Human)
Institute

Curated by ChEMBL
LigandPNGBDBM50224873((6S,11R)-3-cyclopropylmethyl-6,11-dimethyl-1,2,3,4...)
Affinity DataKi:  1.5nMAssay Description:Displacement of [3H]U-69593 from kappa opioid receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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