Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50004213
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium Falciparum)
National Science and Technology Development Agency
Curated by ChEMBL
National Science and Technology Development Agency
Curated by ChEMBL
Affinity DataIC50: 90nMAssay Description:Inhibition of pyrimethamine-resistant form-2 Plasmodium falciparum N51I, C59R, S108N, I164L, K96N mutant expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
3D Structure (crystal)TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium Falciparum)
National Science and Technology Development Agency
Curated by ChEMBL
National Science and Technology Development Agency
Curated by ChEMBL
Affinity DataIC50: 2.48E+3nMAssay Description:Inhibition of pyrimethamine-resistant form-2 Plasmodium falciparum N51I, C59R, S108N, I164L, K96N mutant expressed in Escherichia coli BL21(DE3)More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium Falciparum)
National Science and Technology Development Agency
Curated by ChEMBL
National Science and Technology Development Agency
Curated by ChEMBL
Affinity DataKi: 0.850nMAssay Description:Inhibition of pyrimethamine-resistant form-2 Plasmodium falciparum N51I, C59R, S108N, I164L, K96N mutant expressed in Escherichia coli BL21(DE3) by M...More data for this Ligand-Target Pair
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Plasmodium Falciparum)
National Science and Technology Development Agency
Curated by ChEMBL
National Science and Technology Development Agency
Curated by ChEMBL
Affinity DataKi: 292nMAssay Description:Inhibition of pyrimethamine-resistant form-2 Plasmodium falciparum N51I, C59R, S108N, I164L, K96N mutant expressed in Escherichia coli BL21(DE3) by M...More data for this Ligand-Target Pair
