Compile Data Set for Download or QSAR
Report error Found 26 Enz. Inhib. hit(s) with all data for entry = 50038860
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 4.20nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 8nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 64nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35938(clorfeniramina | gamma-(4-chlorophenyl)-N,N-dimeth...)
Affinity DataIC50: 66nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 74nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 130nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 180nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50084717(CHEMBL120901 | 3-Naphthalen-2-yl-8-oxa-bicyclo[3.2...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetHistamine H1 receptor(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 3.60E+3nMAssay Description:Displacement of [3H]pyrilamine from human histamine receptor subtype 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | KF...)
Affinity DataIC50: 7.80E+3nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | KF...)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | KF...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(KF-A2 | 10-(2-(diethylamino)ethyl)acridin-9(10H)-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]5HT uptake at human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(KF-A2 | 10-(2-(diethylamino)ethyl)acridin-9(10H)-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | KF...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]norepinephrine uptake at human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249783(10-(6-(diethylamino)hexyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249782(10-(5-(diethylamino)pentyl)acridin-9(10H)-one | KF...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249781(10-(4-(diethylamino)butyl)acridin-9(10H)-one | KF-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249780(10-(3-(diethylamino)propyl)acridin-9(10H)-one | KF...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50249759(KF-A2 | 10-(2-(diethylamino)ethyl)acridin-9(10H)-o...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM50010859(CHEMBL11 | Imipramin | IMIPRAMINE HYDROCHLORIDE | ...)
Affinity DataIC50: 2.56E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Veterans Affairs Medical Center

Curated by ChEMBL
LigandPNGBDBM35229(Desmethylimipramine | 3-(10,11-dihydro-5H-dibenzo[...)
Affinity DataIC50: 8.20E+4nMAssay Description:Inhibition of [3H]dopamine uptake at human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed