Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50021139
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM25437(4-{[(1R,2S)-2-cyanocyclohexyl]oxy}-2-(trifluoromet...)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221436(4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzo...)
Affinity DataIC50: 13nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)
Affinity DataIC50: 43nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221436(4-(2-cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzo...)
Affinity DataIC50: 58nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM25437(4-{[(1R,2S)-2-cyanocyclohexyl]oxy}-2-(trifluoromet...)
Affinity DataIC50: 60nMAssay Description:Displacement of [3H]DHT from androgen receptor expressed in Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50221435(4-((trans)-2-cyanocyclohexyloxy)-2-(trifluoromethy...)
Affinity DataIC50: 196nMAssay Description:Antagonist activity at androgen receptor expressed in MDA-MB-453 cells assessed as inhibition of dihydrotestosterone-induced response in reporter gen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed