Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50021083
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220766(5-(7-(4-morpholinobutoxy)-1,4-dihydroindeno[1,2-c]...)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220753(CHEMBL398750 | 5-(6,7-dimethoxy-2,4-dihydro-indeno...)
Affinity DataIC50: 0.810nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220762(5-(7-(3-(1,4-oxazepan-4-yl)propoxy)-1,4-dihydroind...)
Affinity DataIC50: 0.920nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220757(5-(7-(3-(piperidin-4-yl)propoxy)-1,4-dihydroindeno...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220751(5-(7-(3-((2S,6R)-2,6-dimethylmorpholino)propoxy)-1...)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220768(5-(7-(3-(1H-imidazol-1-yl)propoxy)-1,4-dihydroinde...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220755(5-(6-methoxy-7-(2-(4-methylthiazol-5-yl)ethoxy)-1,...)
Affinity DataIC50: 1.10nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220774(5-(7-(4-morpholinobutyl)-1,4-dihydroindeno[1,2-c]p...)
Affinity DataIC50: 1.20nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220765(5-(7-(5-morpholinopentyloxy)-1,4-dihydroindeno[1,2...)
Affinity DataIC50: 1.40nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220752(5-(7-(4-(4-acetylpiperazin-1-yl)butoxy)-1,4-dihydr...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220754(5-(7-(3-(4-methylpiperazin-1-yl)propoxy)-1,4-dihyd...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50214577(Chk1_115 | CHEMBL245796 | 4'-(6,7-dimethoxy-1,4-di...)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220756(5-(7-(2-(2-morpholinoethoxy)ethoxy)-1,4-dihydroind...)
Affinity DataIC50: 1.80nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220761(5-(7-methoxy-6-(2-(4-methylthiazol-5-yl)ethoxy)-1,...)
Affinity DataIC50: 2.5nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220771(5-(7-(3-(piperidin-1-yl)propoxy)-1,4-dihydroindeno...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220778(5-(7-(2-hydroxyethoxy)-6-methoxy-1,4-dihydroindeno...)
Affinity DataIC50: 2.60nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220770(5-(6-methoxy-7-(2-morpholinoethoxy)-1,4-dihydroind...)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220764(5-(6-(2-hydroxyethoxy)-7-methoxy-1,4-dihydroindeno...)
Affinity DataIC50: 3.10nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220772(5-(7-(3-morpholinopropoxy)-1,4-dihydroindeno[1,2-c...)
Affinity DataIC50: 3.20nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220776(5-(7-methoxy-6-(pyridin-2-ylmethoxy)-1,4-dihydroin...)
Affinity DataIC50: 3.70nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220775(5-(7-methoxy-6-(2-morpholinoethoxy)-1,4-dihydroind...)
Affinity DataIC50: 3.80nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220777(5-(7-(2-morpholinoethoxy)-1,4-dihydroindeno[1,2-c]...)
Affinity DataIC50: 5.90nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220769(5-(6-(3-morpholinopropoxy)-1,4-dihydroindeno[1,2-c...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220759(5-(7-(2-(4-methylthiazol-5-yl)ethoxy)-1,4-dihydroi...)
Affinity DataIC50: 6.40nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220760(5-(6-(2-morpholinoethoxy)-1,4-dihydroindeno[1,2-c]...)
Affinity DataIC50: 6.5nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220767(5-(7-(2-morpholinoethylamino)-1,4-dihydroindeno[1,...)
Affinity DataIC50: 7nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220758(N-(3-(6-cyanopyridin-3-yl)-1,4-dihydroindeno[1,2-c...)
Affinity DataIC50: 16nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Chk1(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50220763(5-(7-(3-(thiophen-2-yl)propoxy)-1,4-dihydroindeno[...)
Affinity DataIC50: 52nMAssay Description:Inhibition of recombinant CHK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed