Compile Data Set for Download or QSAR
Report error Found 36 Enz. Inhib. hit(s) with all data for entry = 50037978
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50209683((R)-2-(4-(9-bromo-2,3-dimethylnaphtho[2,3-b]thioph...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220215((5-benzyloxy-3-hydroxy-3'-trifluoromethyl-biphenyl...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of SHP-1 catalytic domain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220221([3-hydroxy-3'-trifluoromethyl-5-(4-trifluoromethyl...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220216([3-hydroxy-4'-trifluoromethyl-5-(4-trifluoromethyl...)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220220((5-benzyloxy-3-hydroxy-3',5'-bis-trifluoromethyl-b...)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of yeast PTP1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220220((5-benzyloxy-3-hydroxy-3',5'-bis-trifluoromethyl-b...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of SHP-1 catalytic domain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220216([3-hydroxy-4'-trifluoromethyl-5-(4-trifluoromethyl...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of SHP-1 catalytic domain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220214((5-benzyloxy-3-hydroxy-4'-trifluoromethyl-biphenyl...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220221([3-hydroxy-3'-trifluoromethyl-5-(4-trifluoromethyl...)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of SHP-1 catalytic domain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220214((5-benzyloxy-3-hydroxy-4'-trifluoromethyl-biphenyl...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of yeast PTP1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220221([3-hydroxy-3'-trifluoromethyl-5-(4-trifluoromethyl...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of yeast PTP1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220223([3-hydroxy-5-(4-trifluoromethyl-benzyloxy)-bipheny...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220220((5-benzyloxy-3-hydroxy-3',5'-bis-trifluoromethyl-b...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of yeast PTP1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220216([3-hydroxy-4'-trifluoromethyl-5-(4-trifluoromethyl...)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of yeast PTP1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220214((5-benzyloxy-3-hydroxy-4'-trifluoromethyl-biphenyl...)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of SHP-1 catalytic domain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220220((5-benzyloxy-3-hydroxy-3',5'-bis-trifluoromethyl-b...)
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220215((5-benzyloxy-3-hydroxy-3'-trifluoromethyl-biphenyl...)
Affinity DataIC50: 3.80E+4nMAssay Description:Inhibition of SHP-1 catalytic domain after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220226([5-(3,5-dimethoxy-benzyloxy)-3-hydroxy-biphenyl-4-...)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220216([3-hydroxy-4'-trifluoromethyl-5-(4-trifluoromethyl...)
Affinity DataIC50: 4.40E+4nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220215((5-benzyloxy-3-hydroxy-3'-trifluoromethyl-biphenyl...)
Affinity DataIC50: 5.20E+4nMAssay Description:Inhibition of yeast PTP1 after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220221([3-hydroxy-3'-trifluoromethyl-5-(4-trifluoromethyl...)
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220219(2-(2-(4-(trifluoromethyl)benzyloxy)-4-bromo-6-hydr...)
Affinity DataIC50: 7.30E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220218((5-benzyloxy-3-hydroxy-biphenyl-4-yloxy)-acetic ac...)
Affinity DataIC50: 9.30E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220214((5-benzyloxy-3-hydroxy-4'-trifluoromethyl-biphenyl...)
Affinity DataIC50: 9.60E+4nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220215((5-benzyloxy-3-hydroxy-3'-trifluoromethyl-biphenyl...)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220224(2-(2-(benzyloxy)-4-bromo-6-hydroxyphenoxy)acetic a...)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220225(2-(2-(benzyloxy)-6-hydroxyphenoxy)acetic acid | CH...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220227((3,5-dihydroxy-biphenyl-4-yloxy)-acetic acid | CHE...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220222(2-(2-(4-(trifluoromethyl)benzyloxy)-6-hydroxypheno...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50220217([3-hydroxy-3',5'-bis-trifluoromethyl-5-(4-trifluor...)
Affinity DataKi:  8.20E+3nMAssay Description:Inhibition of TC-PTP after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed