Compile Data Set for Download or QSAR
Report error Found 61 Enz. Inhib. hit(s) with all data for entry = 50021033
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220180(N-[3-fluoro-4'-(trifluoromethyl)-4-biphenylyl]sulf...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220195(N-[4'-(trifluoromethyl)-4-biphenylyl]thiourea | CH...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220185(1-(3-fluoro-4'-(trifluoromethyl)biphenyl-4-yl)urea...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220159(N-[3'-fluoro-4'-(trifluoromethyl)-4-biphenylyl]sul...)
Affinity DataIC50: 15nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220182(N-[4'-(trifluoromethyl)-4-biphenylyl]sulfamide | C...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220201(N-[3-amino-4'-(trifluoromethyl)-4-biphenylyl]sulfa...)
Affinity DataIC50: 24nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220155(N-[3'-nitro-4'-(trifluoromethyl)-4-biphenylyl]sulf...)
Affinity DataIC50: 28nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220176(N-[4-(2,2-difluoro-1,3-benzodioxol-5-yl)phenyl]sul...)
Affinity DataIC50: 31nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220162(N-[4'-(trifluoromethyl)-4-biphenylyl]urea | CHEMBL...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220188(N-(4'-t-butyl-4-biphenylyl)urea | CHEMBL244126)
Affinity DataIC50: 54nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220192(N-(4'-isopropyl-4-biphenylyl)urea | CHEMBL397249)
Affinity DataIC50: 57nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220177(N-{4'-[(trifluoromethyl)sulfonyl]-4-biphenyl}urea ...)
Affinity DataIC50: 58nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220172(4'-(trifluoromethyl)-4-biphenylyl sulfamate | CHEM...)
Affinity DataIC50: 64nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220209(N-[3-(methoxy)-4'-(trifluoromethyl)-4-biphenylyl]s...)
Affinity DataIC50: 66nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220170(N-[3-Chloro-4'-(trifluoromethyl)-4-biphenylyl]sulf...)
Affinity DataIC50: 67nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220181(N-[4-(2,2,3,3-tetrafluoro-2,3-dihydro-1,4-benzodio...)
Affinity DataIC50: 67nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220174(1-[4'-(trifluoromethyl)-4-biphenylyl]methanesulfon...)
Affinity DataIC50: 118nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220197(N-[3-methyl-4'-(trifluoromethyl)-4-biphenylyl]sulf...)
Affinity DataIC50: 141nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220169(N-[4'-(trifluoromethyl)-4-biphenylyl]methanesulfon...)
Affinity DataIC50: 161nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220157(N-[3'-amino-4'-(trifluoromethyl)-4-biphenylyl]sulf...)
Affinity DataIC50: 167nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220179(N-{4'-[(trifluoromethyl)sulfonyl]-4-biphenylyl}met...)
Affinity DataIC50: 176nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220189(N-[3-cyano-4'-(trifluoromethyl)-4-biphenylyl]sulfa...)
Affinity DataIC50: 196nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220203(N-{4'-[(trifluoromethyl)thio]-4-biphenyl}urea | CH...)
Affinity DataIC50: 240nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220178(N-(4'-bromo-3,3'-difluoro-4-biphenylyl)urea | CHEM...)
Affinity DataIC50: 262nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220166(N-[4-(2,2,4,4-tetrafluoro-4H-1,3-benzodioxin-6-yl)...)
Affinity DataIC50: 319nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220193(4'-(trifluoromethyl)-4-biphenylsulfonamide | CHEMB...)
Affinity DataIC50: 345nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220196(N-[3-hydroxy-4'-(trifluoromethyl)-4-biphenylyl]sul...)
Affinity DataIC50: 349nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220202(N-[4-(2,2-dimethyl-1,3-benzodioxol-5-yl)phenyl]sul...)
Affinity DataIC50: 482nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220210(N-[3,5-difluoro-4'-(trifluoromethyl)-4-biphenylyl]...)
Affinity DataIC50: 502nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220171(N-[2-fluoro-4'-(trifluoromethyl)-4-biphenylyl]sulf...)
Affinity DataIC50: 685nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220207(4'-(trifluoromethyl)-4-biphenylol | CHEMBL244264)
Affinity DataIC50: 700nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220194(4'-(trifluoromethyl)-4-biphenylyl carbamate | CHEM...)
Affinity DataIC50: 716nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220200(N-[4'-(trifluoromethoxy)-4-biphenylyl]methanesulfo...)
Affinity DataIC50: 792nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220206(N-cyano-N'-[4'-(trifluoromethyl)-4-biphenylyl]guan...)
Affinity DataIC50: 840nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220173(N-(4'-methyl-4-biphenylyl)urea | CHEMBL244125)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220163(N-methyl-N-[4'-(trifluoromethyl)-4-biphenylyl]sulf...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220204(N-[3-(methylamino)-4'-(trifluoromethyl)-4-biphenyl...)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220175(4'-trifluoromethyl-biphenyl-4-ylamine | CHEMBL2421...)
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220190(N,N-dimethyl-N'-[4'-(trifluoromethyl)-4-biphenylyl...)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220160(N-(4'-chloro-4-biphenylyl)methanesulfonamide | CHE...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220208(N-[4'-(trifluoromethyl)-4-biphenylyl]ethanesulfona...)
Affinity DataIC50: 2.52E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220158(methyl[4'-(trifluoromethyl)-4-biphenylyl]amine | C...)
Affinity DataIC50: 3.73E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220191(4-(trifluoromethyl)biphenyl | CHEMBL242993)
Affinity DataIC50: 5.32E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220186(N-[4'-(trifluoromethyl)-3-biphenylyl]methanesulfon...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220199(N-[3'-(trifluoromethyl)-4-biphenylyl]urea | CHEMBL...)
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220205(N-[4-(1,3-benzodioxol-5-yl)phenyl]sulfamide | CHEM...)
Affinity DataIC50: 7.68E+3nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220161(N-[4'-(ethylsulfonyl)-3-fluoro-4-biphenylyl]urea |...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220167(N-[4'-(2,2,2-trifluoroethyl)-4-biphenylyl]methanes...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50220212(N-[4-(2,3-dihydro-1,4-benzodioxin-6-yl)phenyl]sulf...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetKinesin-like protein KIF11(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50060996(4'-Trifluoromethyl-biphenyl-4-carboxylic acid | 4'...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human KSP motor domain by ATPase assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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