Compile Data Set for Download or QSAR
Report error Found 22 Enz. Inhib. hit(s) with all data for entry = 50025348
TargetCannabinoid receptor 1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50008022(CHEMBL28045 | (4-methoxyphenyl)(3-morpholinomethyl...)
Affinity DataIC50: 0.320nMAssay Description:Agonist activity at CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataIC50: 2nMAssay Description:Agonist activity at CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50251194(4-(2-(3-(3-Phenyl-1,2,4-oxadiazol-5-yl)-1H-indol-1...)
Affinity DataIC50: 250nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataIC50: 430nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50008029((s-cis) -(4-Methoxy-phenyl)-[2-methyl-1-(2-morphol...)
Affinity DataIC50: 453nMAssay Description:Agonist activity at CB1 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50251193(3-[3-Benzyl-[1,2,4]oxadiazol-5-yl]-1-(2-morpholin-...)
Affinity DataIC50: 1.10E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB2 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50251195(4-(2-(3-(3-Biphenyl-4-yl)-1,2,4-oxadiazol-5-yl)-1H...)
Affinity DataIC50: 1.52E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM21281(WIN55212-2 | CHEMBL188 | (2,3-dihydro-5-methyl-3-(...)
Affinity DataIC50: 2.20E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB2 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50251193(3-[3-Benzyl-[1,2,4]oxadiazol-5-yl]-1-(2-morpholin-...)
Affinity DataIC50: 2.62E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50260494(4-(2-(3-(3-(4-Methoxybenzyl)-1,2,4-oxadiazol-5-yl)...)
Affinity DataIC50: 2.80E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB2 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50251180((6aS,10aS)-9-(hydroxymethyl)-6,6-dimethyl-3-(2-met...)
Affinity DataIC50: 3.22E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataIC50: 3.92E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50251194(4-(2-(3-(3-Phenyl-1,2,4-oxadiazol-5-yl)-1H-indol-1...)
Affinity DataIC50: 4.03E+3nMAssay Description:Displacement of [3H]WIN-55212-2 from CB2 receptor in Sprague-Dawley rat spleen membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50260493(3-Benzyl-5-1-(2-(piperidine-1-yl)ethyl)-1H-indol-3...)
Affinity DataIC50: 5.60E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50260502(4-((3-(3-Benzyl-1,2,4-oxadiazol-5-yl)-1H-indol-1-y...)
Affinity DataIC50: 6.10E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50260495(4-(2-(3-(3-(4-Bromobenzyl)-1,2,4-oxadiazol-5-yl)-1...)
Affinity DataIC50: 6.20E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50260500(4-(2-(3-(3-Phenethyl-1,2,4-oxadiazol-5-yl)-1H-indo...)
Affinity DataIC50: 6.80E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50260484(4-(2-(3-(3-(Thiophen-2-ylmethyl)-1,2,4-oxadiazol-5...)
Affinity DataIC50: 6.80E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50260501(4-(2-(3-(3-(2-Chlorobenzyl)-1,2,4-oxadiazol-5-yl)-...)
Affinity DataIC50: 7.40E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Rat)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50260499(3-Benzyl-5-(1-pentyl-1H-indol-3-yl)-1,2,4-oxadiazo...)
Affinity DataIC50: 8.80E+3nMAssay Description:Displacement of [3H]SR141716A from CB1 receptor in Sprague-Dawley rat cerebellum membraneMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50240606(L-759787 | [2-Methyl-3-(2-morpholin-4-yl-ethyl)-in...)
Affinity DataKi:  8.5nMAssay Description:Activity at CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50234418((2,3-Dichloro-phenyl)-[5-methoxy-2-methyl-3-(2-mor...)
Affinity DataKi:  12nMAssay Description:Activity at CB2 receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed