Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50020636
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215890(1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-t...)
Affinity DataEC50:  6.89E+3nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215897(3-(4-hydroxy-phenyl)-1,2,3,4-tetrahydroquinolin-7-...)
Affinity DataEC50:  9.70E+3nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215891(3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-q...)
Affinity DataEC50:  1.52E+4nMAssay Description:Agonist activity at human ERalpha expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215897(3-(4-hydroxy-phenyl)-1,2,3,4-tetrahydroquinolin-7-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human ERalpha expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215893(3-(4-hydroxyphenyl)quinolin-7-ol | 3-(4-hydroxy-ph...)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human ERalpha expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataEC50:  28nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215894(3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-q...)
Affinity DataEC50:  4.75E+3nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215893(3-(4-hydroxyphenyl)quinolin-7-ol | 3-(4-hydroxy-ph...)
Affinity DataEC50:  3.75E+4nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215892(1-ethyl-3-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-qu...)
Affinity DataEC50:  2.43E+4nMAssay Description:Agonist activity at human ERalpha expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215892(1-ethyl-3-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-qu...)
Affinity DataEC50:  580nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataEC50:  810nMAssay Description:Agonist activity at human ERalpha expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215891(3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-q...)
Affinity DataEC50:  300nMAssay Description:Agonist activity at human ERbeta expressed in yeast AH109 by yeast two hybrid assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 6.80nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215892(1-ethyl-3-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-qu...)
Affinity DataIC50: 83nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215894(3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215891(3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 220nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215890(1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-t...)
Affinity DataIC50: 230nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215896(3-(4-hydroxy-phenyl)-1-methanesulfonyl-1,2,3,4-tet...)
Affinity DataIC50: 520nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM19459(Prunetol | Genisteol | CHEMBL44 | US8552057, 2 | c...)
Affinity DataIC50: 580nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215892(1-ethyl-3-(4-hydroxy-phenyl)-1,2,3,4-tetrahydro-qu...)
Affinity DataIC50: 1.41E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215890(1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-t...)
Affinity DataIC50: 1.63E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215894(3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 2.47E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215894(3-(4-hydroxy-phenyl)-1-propyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 2.65E+3nMAssay Description:Antagonist activity at ERalpha expressed in yeast AH109 assessed as inhibition of 17-beta-estradiol induced alpha-galactosidase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215895(cyclopropyl-[7-hydroxy-3-(4-hydroxy-phenyl)-3,4-di...)
Affinity DataIC50: 2.95E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215891(3-(4-hydroxy-phenyl)-1-methyl-1,2,3,4-tetrahydro-q...)
Affinity DataIC50: 2.95E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor beta(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215898(7-hydroxy-3-(4-hydroxy-phenyl)-3,4-dihydro-1H-quin...)
Affinity DataIC50: 4.90E+3nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERbetaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215890(1-cyclopropylmethyl-3-(4-hydroxy-phenyl)-1,2,3,4-t...)
Affinity DataIC50: 5.57E+3nMAssay Description:Antagonist activity at ERalpha expressed in yeast AH109 assessed as inhibition of 17-beta-estradiol induced alpha-galactosidase activityMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEstrogen receptor(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50215896(3-(4-hydroxy-phenyl)-1-methanesulfonyl-1,2,3,4-tet...)
Affinity DataIC50: 3.21E+4nMAssay Description:Displacement of [3H]17beta-estradiol from recombinant human ERalphaMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed