Compile Data Set for Download or QSAR
Report error Found 60 Enz. Inhib. hit(s) with all data for entry = 50020595
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215423(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 20nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215433(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215423(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 40nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215433(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 50nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215425(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 60nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215426(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 110nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215421(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215436(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 790nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215427(N-(4-(aminomethyl)benzyl)-2-(6-(3-aminophenyl)-5-c...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215428(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 5.48E+3nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215435(N-{[4-(N-aminocarbamimidoyl)phenyl]methyl}-2-[6-(3...)
Affinity DataIC50: 7.02E+3nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215423(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 1.06E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215432(N-{2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamin...)
Affinity DataIC50: 1.07E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215437(N-((3-aminobenzo[d]isoxazol-6-yl)methyl)-2-(6-(3-a...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215422(N-(4-(4,5-dihydro-1H-imidazol-2-yl)benzyl)-2-(6-(3...)
Affinity DataIC50: 1.25E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215433(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215431(N-((3-aminobenzo[d]isothiazol-6-yl)methyl)-2-(6-(3...)
Affinity DataIC50: 2.68E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215438((E)-N-((5-amino-2,3-dihydrobenzo[f][1,4]thiazepin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215436(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215438((E)-N-((5-amino-2,3-dihydrobenzo[f][1,4]thiazepin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215419(N-((1-amino-4-oxo-3,4-dihydrophthalazin-6-yl)methy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215424(N-((1-aminoisoquinolin-6-yl)methyl)-2-(6-(3-aminop...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215438((E)-N-((5-amino-2,3-dihydrobenzo[f][1,4]thiazepin-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215432(N-{2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215434(N-(2-(1H-imidazol-5-yl)ethyl)-2-(6-(3-aminophenyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215429(N-(2-(2-amino-1H-imidazol-5-yl)ethyl)-2-(6-(3-amin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215425(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215436(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215430(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215437(N-((3-aminobenzo[d]isoxazol-6-yl)methyl)-2-(6-(3-a...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215419(N-((1-amino-4-oxo-3,4-dihydrophthalazin-6-yl)methy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215427(N-(4-(aminomethyl)benzyl)-2-(6-(3-aminophenyl)-5-c...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215437(N-((3-aminobenzo[d]isoxazol-6-yl)methyl)-2-(6-(3-a...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215428(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215434(N-(2-(1H-imidazol-5-yl)ethyl)-2-(6-(3-aminophenyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215420(4-({2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylami...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215430(2-(6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215431(N-((3-aminobenzo[d]isothiazol-6-yl)methyl)-2-(6-(3...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215425(2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamino)-...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215429(N-(2-(2-amino-1H-imidazol-5-yl)ethyl)-2-(6-(3-amin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215429(N-(2-(2-amino-1H-imidazol-5-yl)ethyl)-2-(6-(3-amin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215432(N-{2-[6-(3-aminophenyl)-5-chloro-3-(cyclobutylamin...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215424(N-((1-aminoisoquinolin-6-yl)methyl)-2-(6-(3-aminop...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215422(N-(4-(4,5-dihydro-1H-imidazol-2-yl)benzyl)-2-(6-(3...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor VII(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215419(N-((1-amino-4-oxo-3,4-dihydrophthalazin-6-yl)methy...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 7aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215424(N-((1-aminoisoquinolin-6-yl)methyl)-2-(6-(3-aminop...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215422(N-(4-(4,5-dihydro-1H-imidazol-2-yl)benzyl)-2-(6-(3...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215434(N-(2-(1H-imidazol-5-yl)ethyl)-2-(6-(3-aminophenyl)...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215427(N-(4-(aminomethyl)benzyl)-2-(6-(3-aminophenyl)-5-c...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProthrombin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50215431(N-((3-aminobenzo[d]isothiazol-6-yl)methyl)-2-(6-(3...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of factor 2aMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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