Compile Data Set for Download or QSAR
Report error Found 41 Enz. Inhib. hit(s) with all data for entry = 50020466
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214268((5R,8R,11S)-8-(propan-2-yl)-11-(pyrrolidin-1-ylmet...)
Affinity DataIC50: 2nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214266((5R,8R,11S)-11-[(methylamino)methyl]-8-(propan-2-y...)
Affinity DataIC50: 3nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214272((5R,8R,11S)-11-(aminomethyl)-8-(propan-2-yl)-5-{[3...)
Affinity DataIC50: 8nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214264(1-{[(5R,8R,11S)-6,9,12-trioxo-8-(propan-2-yl)-5-{[...)
Affinity DataIC50: 28nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214262((5R,8R,11S)-5-[(4-chlorophenyl)methyl]-11-[(methyl...)
Affinity DataIC50: 33nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214260((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-8-(propan-2...)
Affinity DataIC50: 56nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50199365((E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl...)
Affinity DataIC50: 74nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214251((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-11-[(dimeth...)
Affinity DataIC50: 95nMAssay Description:Antagonist activity against human motilin receptor in aequoscreen cells assessed as inhibition of motilin induced calcium release by aequorin assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214268((5R,8R,11S)-8-(propan-2-yl)-11-(pyrrolidin-1-ylmet...)
Affinity DataKi:  4.60nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214264(1-{[(5R,8R,11S)-6,9,12-trioxo-8-(propan-2-yl)-5-{[...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214266((5R,8R,11S)-11-[(methylamino)methyl]-8-(propan-2-y...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214270(1-{[(5R,8R,11S)-5-[(4-chlorophenyl)methyl]-6,9,12-...)
Affinity DataKi:  6nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214272((5R,8R,11S)-11-(aminomethyl)-8-(propan-2-yl)-5-{[3...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214250((5R,8R,11S)-5-[(4-chlorophenyl)methyl]-11-[(dimeth...)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214255((5R,8R,11S)-11-[(5-methyl-1H-1,2,3-triazol-1-yl)me...)
Affinity DataKi:  17nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214260((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-8-(propan-2...)
Affinity DataKi:  18nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214253((5R,8R,11S)-8-(propan-2-yl)-11-[(pyrimidin-2-ylami...)
Affinity DataKi:  20nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214274((5R,8R,11S)-11-[(5-methyl-1H-1,2,3,4-tetrazol-1-yl...)
Affinity DataKi:  21nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214261((5R,8R,11S)-11-[(4,5-dimethyl-1H-1,2,3-triazol-1-y...)
Affinity DataKi:  23nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214276(3-[(5R,8R,11S)-5-[(3-chlorophenyl)methyl]-6,9,12-t...)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214251((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-11-[(dimeth...)
Affinity DataKi:  27nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214262((5R,8R,11S)-5-[(4-chlorophenyl)methyl]-11-[(methyl...)
Affinity DataKi:  31nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214267(1-{2-[(5R,8R,11S)-5-[(3-chlorophenyl)methyl]-6,9,1...)
Affinity DataKi:  33nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214273((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-8-(propan-2...)
Affinity DataKi:  41nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214257((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-11-[(4,5-di...)
Affinity DataKi:  51nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214269(1-{[(5R,8R,11S)-5-[(3-chlorophenyl)methyl]-6,9,12-...)
Affinity DataKi:  57nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214275((5R,8R,11S)-11-(aminomethyl)-5-[(4-chlorophenyl)me...)
Affinity DataKi:  60nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214254((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-11-(1H-imid...)
Affinity DataKi:  62nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214278((5R,8R,11S)-11-(aminomethyl)-5-[(3-chlorophenyl)me...)
Affinity DataKi:  64nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214279((5R,8R,11S)-5-[(3-chlorophenyl)methyl]-8-(propan-2...)
Affinity DataKi:  87nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214263(1-{[(5R,8R,11S)-5-[(3-chlorophenyl)methyl]-6,9,12-...)
Affinity DataKi:  100nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214256((5R,8R,11S)-5-[(3-fluorophenyl)methyl]-8-(propan-2...)
Affinity DataKi:  116nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50199365((E)-(9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl...)
Affinity DataKi:  137nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214258((5R,8R,11S)-11-(aminomethyl)-5-[(4-hydroxyphenyl)m...)
Affinity DataKi:  171nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214265((5R,8R,11S)-11-(2-aminoethyl)-5-[(4-hydroxyphenyl)...)
Affinity DataKi:  342nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214259((5R,8R,11S)-5-[(4-hydroxyphenyl)methyl]-8-(propan-...)
Affinity DataKi:  376nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214271({[(5R,8R,11S)-5-[(4-chlorophenyl)methyl]-6,9,12-tr...)
Affinity DataKi:  543nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50199378((9R,12R,15S)-15-(4-amino-butyl)-9-(4-hydroxy-benzy...)
Affinity DataKi:  664nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214252((5R,8R,11S)-11-(3-aminopropyl)-5-[(4-hydroxyphenyl...)
Affinity DataKi:  889nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50214277(N-{[(5R,8R,11S)-5-[(4-hydroxyphenyl)methyl]-6,9,12...)
Affinity DataKi:  1.95E+3nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMotilin receptor(Human)
Tranzyme Pharma

Curated by ChEMBL
LigandPNGBDBM50199382((9R,12R,15S)-9-(4-hydroxy-benzyl)-12-isopropyl-10,...)
Affinity DataKi:  2.55E+3nMAssay Description:Displacement of [125I]motilin from human motilin receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed