Compile Data Set for Download or QSAR
Report error Found 78 Enz. Inhib. hit(s) with all data for entry = 50020350
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(N-(1-(3-aminopropyl)-5-(N-methylcyclohexanecarboxa...)
Affinity DataIC50: 25nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212789(1-(5-amino-5-oxopentyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212761(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(o...)
Affinity DataIC50: 62nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212770(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(n...)
Affinity DataIC50: 69nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212760(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(4...)
Affinity DataIC50: 76nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212788(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50: 81nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212776(N-cyclohexyl-1-(3-hydroxypropyl)-N-methyl-2-(thiop...)
Affinity DataIC50: 92nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212778(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212795(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(3-fluorobe...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(N-(1-(3-aminopropyl)-5-(N-methylcyclohexanecarboxa...)
Affinity DataIC50: 110nMAssay Description:Inhibition of human ITK in presence of 3 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212783(1-(4-amino-4-oxobutyl)-N-cyclohexyl-N-methyl-2-(th...)
Affinity DataIC50: 140nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212773(N-cyclohexyl-N-methyl-1-(3-(methylamino)-3-oxoprop...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212785(N-cyclohexyl-1-(2-hydroxyethyl)-N-methyl-2-(thioph...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212771(1-(3-amino-3-oxopropyl)-2-(4-cyanobenzamido)-N-cyc...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212779(ethyl 3-(5-(cyclohexyl(methyl)carbamoyl)-2-(thioph...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212772(N-allyl-1-(3-amino-3-oxopropyl)-2-(4-bromobenzamid...)
Affinity DataIC50: 230nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212794(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-fluorobe...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212781(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50: 260nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(N-(1-(3-aminopropyl)-5-(N-methylcyclohexanecarboxa...)
Affinity DataIC50: 320nMAssay Description:Inhibition of human ITK in presence of 20 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212767(1-(3-amino-3-oxopropyl)-2-benzamido-N-methyl-N-phe...)
Affinity DataIC50: 330nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212777(1-(3-amino-3-oxopropyl)-2-benzamido-N-cyclohexyl-N...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212774(1-(3-amino-3-oxopropyl)-2-benzamido-N-cyclohexyl-N...)
Affinity DataIC50: 390nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212763(3-(3-aminopropyl)-N-cyclohexyl-N-methyl-2-(thiophe...)
Affinity DataIC50: 710nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212790(N-allyl-1-(3-amino-3-oxopropyl)-2-benzamido-N-cycl...)
Affinity DataIC50: 730nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212766(N-cyclohexyl-N-methyl-1-propyl-2-(thiophene-2-carb...)
Affinity DataIC50: 760nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212787(1-(3-aminopropyl)-N-cyclohexyl-N-methyl-2-(thiophe...)
Affinity DataIC50: 950nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212775(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-methoxyb...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212788(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50: 1.20E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212772(N-allyl-1-(3-amino-3-oxopropyl)-2-(4-bromobenzamid...)
Affinity DataIC50: 1.20E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212781(1-(3-amino-3-oxopropyl)-2-(4-bromobenzamido)-N-cyc...)
Affinity DataIC50: 1.20E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212769(N-cyclohexyl-N-methyl-1-phenethyl-2-(thiophene-2-c...)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase TXK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(N-(1-(3-aminopropyl)-5-(N-methylcyclohexanecarboxa...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of TXKMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212780(N-(1-(3-aminopropyl)-1H-benzo[d]imidazol-2-yl)thio...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(N-(1-(3-aminopropyl)-5-(N-methylcyclohexanecarboxa...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human ITK in presence of 100 uM ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212766(N-cyclohexyl-N-methyl-1-propyl-2-(thiophene-2-carb...)
Affinity DataIC50: 1.60E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212765(N-(1-(3-aminopropyl)-5-(cyclohexanecarboxamido)-1H...)
Affinity DataIC50: 1.70E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212769(N-cyclohexyl-N-methyl-1-phenethyl-2-(thiophene-2-c...)
Affinity DataIC50: 1.80E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212776(N-cyclohexyl-1-(3-hydroxypropyl)-N-methyl-2-(thiop...)
Affinity DataIC50: 2.00E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212764(N-(1-(3-aminopropyl)-5-(N-methylcyclohexanecarboxa...)
Affinity DataIC50: 2.40E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212765(N-(1-(3-aminopropyl)-5-(cyclohexanecarboxamido)-1H...)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212767(1-(3-amino-3-oxopropyl)-2-benzamido-N-methyl-N-phe...)
Affinity DataIC50: 2.60E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212792(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(2...)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212770(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(n...)
Affinity DataIC50: 2.70E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212778(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50: 2.70E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212789(1-(5-amino-5-oxopentyl)-N-cyclohexyl-N-methyl-2-(t...)
Affinity DataIC50: 3.10E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212794(1-(3-amino-3-oxopropyl)-N-cyclohexyl-2-(4-fluorobe...)
Affinity DataIC50: 4.10E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212761(1-(3-amino-3-oxopropyl)-N-cyclohexyl-N-methyl-2-(o...)
Affinity DataIC50: 4.10E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212785(N-cyclohexyl-1-(2-hydroxyethyl)-N-methyl-2-(thioph...)
Affinity DataIC50: 4.60E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212783(1-(4-amino-4-oxobutyl)-N-cyclohexyl-N-methyl-2-(th...)
Affinity DataIC50: 4.60E+3nMAssay Description:Effect on human ITK in DT40 cells assessed as induction of calcium influx by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ITK/TSK(Human)
Boehringer Ingelheim Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50212782(N-cyclohexyl-N-methyl-2-(thiophene-2-carboxamido)-...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human ITK by DELFIA assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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