Compile Data Set for Download or QSAR
Report error Found 39 Enz. Inhib. hit(s) with all data for entry = 50020055
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209900(3-(({7-[amino(imino)methyl]-2-naphthyl}methyl)-{1-...)
Affinity DataIC50: 8.10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209891([(((E)-3-{3-[amino(imino)methyl]phenyl}prop-2-en-1...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209893(7-({[1-(2,5-dimethoxy-benzenesulfonyl)-piperidin-4...)
Affinity DataIC50: 11nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209895(N-({7-[amino(imino)methyl]-2-naphthyl}methyl)-N-{1...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209899(3-(((E)-3-{3-[amino(imino)methyl]phenyl}prop-2-en-...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209904([(({7-[amino(imino)methyl]-2-naphthyl}methyl){1-[(...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209920(7-({[1-(5-chloro-2-methoxy-benzenesulfonyl)-piperi...)
Affinity DataIC50: 39nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: 40nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209915(7-({[1-(3-chloro-benzenesulfonyl)-piperidin-4-yl]-...)
Affinity DataIC50: 49nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209896(7-({methanesulfonyl-[1-(2-methoxy-5-methyl-benzene...)
Affinity DataIC50: 58nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209914(7-({[1-(2,5-dichloro-benzenesulfonyl)-piperidin-4-...)
Affinity DataIC50: 65nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209905(7-{[(methylsulfonyl)(1-pyridin-4-ylpiperidin-4-yl)...)
Affinity DataIC50: 90nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209908(7-({[1-(2,5-dichloro-thiophene-3-sulfonyl)-piperid...)
Affinity DataIC50: 100nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209911(7-({[1-(3-cyano-benzenesulfonyl)-piperidin-4-yl]-m...)
Affinity DataIC50: 170nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209916(7-({[1-(3,4-dichloro-benzenesulfonyl)-piperidin-4-...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209917(7-({[1-(biphenyl-3-sulfonyl)-piperidin-4-yl]-metha...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209894(7-({methanesulfonyl-[1-(toluene-3-sulfonyl)-piperi...)
Affinity DataIC50: 250nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209912(7-({[1-(2-chloro-benzenesulfonyl)-piperidin-4-yl]-...)
Affinity DataIC50: 350nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209921(7-({[1-(2,3-dichloro-benzenesulfonyl)-piperidin-4-...)
Affinity DataIC50: 560nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209901(7-{[{1-[(2,5-dimethoxyphenyl)sulfonyl]piperidin-4-...)
Affinity DataIC50: 590nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209918(7-({[1-(3-fluoro-benzenesulfonyl)-piperidin-4-yl]-...)
Affinity DataIC50: 800nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209897(7-{[(1-benzenesulfonyl-piperidin-4-yl)-methanesulf...)
Affinity DataIC50: 850nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209903(7-({methanesulfonyl-[1-(toluene-2-sulfonyl)-piperi...)
Affinity DataIC50: 950nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209919(7-({[1-(4-chloro-benzenesulfonyl)-piperidin-4-yl]-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209892(7-({[1-(3-chloro-benzyl)-piperidin-4-yl]-methanesu...)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209909(7-({[1-(3-cyano-benzyl)-piperidin-4-yl]-methanesul...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209893(7-({[1-(2,5-dimethoxy-benzenesulfonyl)-piperidin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209906(7-({methanesulfonyl-[1-(toluene-4-sulfonyl)-piperi...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209907(7-{[methanesulfonyl-(1-methanesulfonyl-piperidin-4...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209910(7-({[1-(3-chloro-benzoyl)-piperidin-4-yl]-methanes...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209913(7-({[1-(2,6-dichloro-benzenesulfonyl)-piperidin-4-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209904([(({7-[amino(imino)methyl]-2-naphthyl}methyl){1-[(...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209899(3-(((E)-3-{3-[amino(imino)methyl]phenyl}prop-2-en-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM17283((2S)-3-(7-carbamimidoylnaphthalen-2-yl)-2-(4-{[(3S...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209895(N-({7-[amino(imino)methyl]-2-naphthyl}methyl)-N-{1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209891([(((E)-3-{3-[amino(imino)methyl]phenyl}prop-2-en-1...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209898(7-({[1-(3-cyano-benzoyl)-piperidin-4-yl]-methanesu...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209900(3-(({7-[amino(imino)methyl]-2-naphthyl}methyl)-{1-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human thrombinMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Astellas Pharma

Curated by ChEMBL
LigandPNGBDBM50209902(7-[(methanesulfonyl-piperidin-4-yl-amino)-methyl]-...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed