Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 2469
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20977(CHEMBL186097 | 8-[butyl(ethyl)amino]-4-(2,6-dimeth...)
Affinity DataIC50: 0.820nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20973(CHEMBL189089 | 8-[butyl(ethyl)amino]-4-(4-methoxy-...)
Affinity DataIC50: 0.920nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20978(N-butyl-4-(2,6-dimethoxypyridin-3-yl)-N-ethyl-6-me...)
Affinity DataIC50: 2.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20985(4-{8-[butyl(ethyl)amino]-6-methyl-2-oxo-1H,2H,3H,4...)
Affinity DataIC50: 3.30nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20986(4-{8-[butyl(ethyl)amino]-6-methyl-1H,2H,3H,4H-pyri...)
Affinity DataIC50: 3.5nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20974(N-butyl-N-ethyl-4-(4-methoxy-2-methylphenyl)-6-met...)
Affinity DataIC50: 4.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20989(8-[butyl(ethyl)amino]-4-(4-acetyl-2-methylphenyl)-...)
Affinity DataIC50: 5.80nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20990(1-(4-{8-[butyl(ethyl)amino]-6-methyl-1H,2H,3H,4H-p...)
Affinity DataIC50: 8.20nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20980(N-butyl-8-(2,6-dimethoxypyridin-3-yl)-N-ethyl-2-me...)
Affinity DataIC50: 9.90nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20976(N-butyl-N-ethyl-8-(4-methoxy-2-methylphenyl)-2-met...)
Affinity DataIC50: 11.7nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20981(4-(4,5-dimethoxy-2-methylphenyl)-8-[(2-methoxyethy...)
Affinity DataIC50: 43nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20979(4-[butyl(ethyl)amino]-8-(2,6-dimethoxypyridin-3-yl...)
Affinity DataIC50: 60nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20982(4-(4,5-dimethoxy-2-methylphenyl)-N-(2-methoxyethyl...)
Affinity DataIC50: 87nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20975(4-[butyl(ethyl)amino]-8-(4-methoxy-2-methylphenyl)...)
Affinity DataIC50: 95nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20988(4-{4-[butyl(ethyl)amino]-2-methyl-5,6,7,8-tetrahyd...)
Affinity DataIC50: 102nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20992(1-(4-{4-[butyl(ethyl)amino]-2-methyl-5,6,7,8-tetra...)
Affinity DataIC50: 172nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20984(8-(4,5-dimethoxy-2-methylphenyl)-N-(2-methoxyethyl...)
Affinity DataIC50: 210nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20987(4-{4-[butyl(ethyl)amino]-2-methyl-6-oxo-5,6,7,8-te...)
Affinity DataIC50: 573nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20991(4-[butyl(ethyl)amino]-8-(4-acetyl-2-methylphenyl)-...)
Affinity DataIC50: 713nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Rat)
Bristol-Myers Squibb

LigandPNGBDBM20983(8-(4,5-dimethoxy-2-methylphenyl)-4-[(2-methoxyethy...)
Affinity DataIC50: 3.11E+3nMpH: 7.0 T: 2°CAssay Description:The IC50 values were measured by monitoring the inhibition effects of test compounds on [125I]-o-CRF binding to rat cortex in vitro. More data for this Ligand-Target Pair
In DepthDetails Article
PubMed