Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50019937
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209010(3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50036210((2S,3S)-3-Carboxy-2,3-dihydroxy-pentanedioic acid ...)
Affinity DataIC50: 150nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209015(3,5-dichloro-2-hydroxy-N-(2,4,6-triphenylphenyl)be...)
Affinity DataIC50: 190nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209014((Z)-3-phenylallyl 2-(3,5-dichloro-2-hydroxyphenyls...)
Affinity DataIC50: 340nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209009(2-isopropyl-5-methylcyclohexyl 2-(3,5-dichloro-2-h...)
Affinity DataIC50: 370nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209018(3,5-dichloro-N-(3,5-di-tert-butylphenyl)-2-hydroxy...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50066683((S)-2-[(R)-8-(2,4-Dichloro-phenyl)-2-hydroxy-octyl...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209013(3,5-dichloro-N-(3,5-dichlorophenyl)-2-hydroxybenze...)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209008(3,5-dichloro-N-(2,5-di-tert-butylphenyl)-2-hydroxy...)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 1(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209010(3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of human ACC1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209012(3,5-dichloro-N-(4-hexylphenyl)-2-hydroxybenzenesul...)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209007(3,5-dichloro-N-(3,5-difluorophenyl)-2-hydroxybenze...)
Affinity DataIC50: 7.60E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209017(3,5-dichloro-2-hydroxy-N-(3-phenoxyphenyl)benzenes...)
Affinity DataIC50: 8.10E+3nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetATP-citrate synthase(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209011(N-(4-(3,5-dichloro-2-hydroxyphenylsulfonamido)phen...)
Affinity DataIC50: 1.09E+4nMAssay Description:Inhibition of human recombinant ATP-citrate lyaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetAcetyl-CoA carboxylase 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50209010(3,5-dichloro-2-hydroxy-N-(4-methoxy-biphenyl-3-yl)...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human ACC2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed