Compile Data Set for Download or QSAR
Report error Found 24 Enz. Inhib. hit(s) with all data for entry = 50037940
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50209683((R)-2-(4-(9-bromo-2,3-dimethylnaphtho[2,3-b]thioph...)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208362(3-benzyl-5-[(5-benzyl-3-carboxy-4-hydroxycyclohexa...)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5-(3-carboxy-4-hydroxy-4-phenyl-benzyl)-2-hydroxy-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208362(3-benzyl-5-[(5-benzyl-3-carboxy-4-hydroxycyclohexa...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of SHP-1 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208360(5-((3-carboxy-5-(furan-2-yl)-4-hydroxycyclohexa-1,...)
Affinity DataIC50: 3.90E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5-(3-carboxy-4-hydroxy-4-phenyl-benzyl)-2-hydroxy-...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of SHP-1 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208364(3-bromo-5-(3-bromo-5-carboxy-4-hydroxybenzyl)-2-hy...)
Affinity DataIC50: 7.80E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208362(3-benzyl-5-[(5-benzyl-3-carboxy-4-hydroxycyclohexa...)
Affinity DataIC50: 1.03E+5nMAssay Description:Inhibition of yeast PTP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208362(3-benzyl-5-[(5-benzyl-3-carboxy-4-hydroxycyclohexa...)
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase 1(Baker's yeast)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5-(3-carboxy-4-hydroxy-4-phenyl-benzyl)-2-hydroxy-...)
Affinity DataIC50: 2.34E+5nMAssay Description:Inhibition of yeast PTP1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50048522(5-(3-carboxy-5-chloro-4-hydroxybenzyl)-3-chloro-2-...)
Affinity DataIC50: 2.42E+5nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5-(3-carboxy-4-hydroxy-4-phenyl-benzyl)-2-hydroxy-...)
Affinity DataIC50: 2.91E+5nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208363(5-(3-carboxy-4-hydroxy-5-methoxybenzyl)-2-hydroxy-...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50056920(5-(3-carboxy-4-hydroxy-5-methylbenzyl)-2-hydroxy-3...)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM11979(MgrA inhibitor, 1 | CHEMBL115145 | 5-[(3-carboxy-4...)
Affinity DataIC50: 3.60E+6nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50209683((R)-2-(4-(9-bromo-2,3-dimethylnaphtho[2,3-b]thioph...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208362(3-benzyl-5-[(5-benzyl-3-carboxy-4-hydroxycyclohexa...)
Affinity DataKi:  6.30E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5-(3-carboxy-4-hydroxy-4-phenyl-benzyl)-2-hydroxy-...)
Affinity DataKi:  9.40E+3nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50118792(2-(carboxyformamido)-4,5,6,7-tetrahydrothieno[2,3-...)
Affinity DataKi:  1.15E+4nMAssay Description:Inhibition of PTP1B after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208362(3-benzyl-5-[(5-benzyl-3-carboxy-4-hydroxycyclohexa...)
Affinity DataKi:  1.40E+4nMAssay Description:Inhibition of SHP-1 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 6(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5-(3-carboxy-4-hydroxy-4-phenyl-benzyl)-2-hydroxy-...)
Affinity DataKi:  1.70E+4nMAssay Description:Inhibition of SHP-1 catalytic domainMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208362(3-benzyl-5-[(5-benzyl-3-carboxy-4-hydroxycyclohexa...)
Affinity DataKi:  2.50E+4nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Human)
Inha University

Curated by ChEMBL
LigandPNGBDBM50208359(5-(3-carboxy-4-hydroxy-4-phenyl-benzyl)-2-hydroxy-...)
Affinity DataKi:  6.40E+4nMAssay Description:Inhibition of TC-PTPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed